Structure of PDB 4v8m Chain Bd Binding Site BS01

Receptor Information
>4v8m Chain Bd (length=70) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKSKNHTNHNQSRKNHRNGIKPPLPLYMYNSKRGGWLPALVNTRRVRKNN
QKAALKARRERLAAHQAAQK
Ligand information
>4v8m Chain BA (length=1847) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaccugaguguggcaggaccacccgcuaaacuuaagcauauuacucag
cggaggaaaagaaaacaaccgugauucucucagucagcggcgagcgaaga
gggauucaacucguugccgaaucgggucuuauaugaccucgaacuguggc
accauuuuuguggccguucuuauagggcuggugcaggcguggcggaauuc
aauugcaaagcaaacccguugcugaacacauuuacaacccuucaugugag
uauugagccaaagaaggugucagcccauuacauuccuuagccacggagcc
uacgcgccuccucauguucgguccaagagaguagcacuguuugggaaugc
agugucaagccggcagguauuugucugccaagguuaaauauagaguagga
agaccgauagcgaacaaguagcgugagcgaaaguuugaaaaguacuuugg
aaagagagugacauagaaccugaaaucgugacaacgacaauggaaguacc
uucauuucuuuuuuuuacggccagacccaaccucgccgcgcaauuucggu
ucaacauccuucacugugcggguuucucuuuugaggucauggggugcgug
agugggcggaauaaagggucgguguguuguguguggguuuuuucucucac
ucucuuccuccuucccuguucgugcgucucgacgcuggcgauggaaaugg
ggugcccccacccgucuugaaacacggaccaaggagucaaacagacgcgc
aagggaggaguauguaugugagaacucuuuucucguacugaaagggagag
ugugauuuuacacccguggcgugcgcaauuucucuuuuuuguguuuuugc
ccaacgccggccggccccccgugggcugcgcgcgagugugccuguuugga
cccgaaagguggugaacuaugccugaacaaggugaagcccggggaaaccc
cgguggaggccuguagcgaugcugacgugcaaaucgcucguacgauuugg
guaucggagcgaaagacucaucgaaccaccuaguagcugguucacgucga
aguuucccucaggauagcuggugcuugucuuuaagaaguauugugcggua
aagcaaaugauuagaggcauugguguucuuguaauaucgaccuauucuca
aacuuuaaaugugcaaacaacccagccuuaguuauuuuaacaaggcuuuu
ggguacauaagaauugaggcaccaagugggccuucuucgguaagcggagc
aggcgaugcggaaugaaccgcuuagggauauguggcgucaaaacuugugg
gcucauucucgauacgugaaaaggguguugguggauagggacaguuggac
gguggccauggaagucggcauccgcuaaggaguguguaacaacucaccaa
ccgaauccaccggccccgaaaauggaugacgcuuaagccccaugugcgug
auugcccauuauuccuuuggugagggcggcuauauuucuuugugagaaag
uguagcccucccgauguagacguggcgugggggugaggacgaagccgaug
gcgcgagccucggauggacccgccucuagugcagaucuugguuggcguag
caaagaucuaacggaauauuuuuucuuaaaugcaacguuggauacuggag
cggggaaggauuucgugccaacggcacucguacacgaguuguucggucac
ugagcacaacguuacaccguuuuguuaggaaagugaagguggucggcgca
caucucccuuuuuugggguuuguguguuuuaccggcuuaucugaaaaggg
gcaacagagaaccugggaugauauuccaaaaagaaauugcauguggg
........................<<<<<.....<......>......>>
>>>...........<......>...<<<<<......<<.....>>....>
>>>>....<<<............<<<<<......>>>>>...........
................<<..<..<<<<..<<<<<<<<.<<<<<.......
.<.<<...<<<<<.....>>>>>....<<<<............>>>>...
>>.>..(........<<......)>>.............>>>>>....>>
>..>>>>>>>>>...>...>>............<<<<<<<........>>
>>>>>......<<<<<........>>>>>..>>>................
....................<<....>>................<<<...
...>>>...................................<<..<<<<.
..<<<<<....<..<<.....<<..<.<<.....<.<<<<<<.<......
............>.>>>>>..>.>.......>>.>....>>.........
.......<<<.<....<<..<.........<<<.<<<......>>>.>>>
..........>..>>..>>>>...............>>.>....>>>>>.
.>>>>..>>..<<<<........>>>><<<<<<.....<<.<<<.<<<<<
..<<<...<<................>>...>>>...<<....>>....<
<<<<....>>>>>...<<<...<<<<<<..........>>>>>>......
>>>.<<<<<<<<...........>>>>>.>>>...>>>>>.>>>.>>...
<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<.<<<....>>>
.>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>>>>
>>>>...<<.......>>......>>>>>>......>.>>...<<<<<..
....<<<....>>><.<.<<<<<<<.........<<....<<<<<<<...
<<<....<<<..<.<<<....<<<<<<.....>>>>>>..>>>.>..>>>
..>>.>...>>>>>>>...<<<<<<<<<<.<<.......>>>>>>>>...
>>>>.........>>..>>>>>>>..>>.<<<<.<<<<<.....>>>>>.
>>>>...<<<<......>>>>..<<<<<<<...<<<(((.........<<
<<........<...........<<<.<<<<<<<<<........<<<<<.<
<....<<.........>>....>>.........<<......>>...>>>>
>....>>>>>>>>>>>>..........))).>....>>>>..........
...>>>...>>>>>>><<<<.<<<<<.....<<<<..............>
>>>..>>>>>>>>>....>>>>>.....<<<<<<..<.......<<<..<
<<....>>>.>>>......>.>>>>>>.........>>>>>>........
......<<<<<<......<<........>>......>>>>>>........
............<<<<<....<<.....>>..>>>>>....<<......<
...<<..<<<<......>>>>..........<<..<<<.<<<<.<.<<<<
<<..<<<<......>>>>..>>>>>>..>.>>>>.>>>..>>........
>>....>.....<<<...........>....>>.>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v8m High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Resolution5.57 Å
Binding residue
(original residue number in PDB)		K3 K5 N6 H7 T8 N9 N11 Q12 K15 H17 R18 N19 L25 Y28 M29 Y30 N31 S32 K33 N43 R46 V47 N51 K53 A55 K57 R60 E61 R62
Binding residue
(residue number reindexed from 1)		K2 K4 N5 H6 T7 N8 N10 Q11 K14 H16 R17 N18 L24 Y27 M28 Y29 N30 S31 K32 N42 R45 V46 N50 K52 A54 K56 R59 E60 R61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v8m, PDBe:4v8m, PDBj:4v8m
PDBsum4v8m
PubMed23395961
UniProtQ383S6

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