Structure of PDB 7nqh Chain Ba Binding Site BS01

Receptor Information
>7nqh Chain Ba (length=393) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYEWGVRSTRKPEPPPLDRVYEIPGLEPITYAGKMHFMPGLARPVFPPWD
PGWTHPKFRRLPPLHEHPLYKDQACYVFHQRCRLLEGVKQALWLTKTQLI
EGLPEKVLRLADDPRNHIENQDERVLNAISHARLWHSTEDIPKRETYCPV
IVDSLIQLCKSQILKHPSLARRICAQNNTLSATWNRESILLQVHGSSGAR
LNAKDPLPPVASQEEVEATKNHVLETFYPISPTMGLQECNVYDVNDDTGF
QEGYPYPCPHTLYFLESANLRPRRFQPDQLRAKMILFAFGSALAQARLLY
GNDSKVLEQPVVVQSVGTDGRLFQFLVLQLNTTDLASDEGVKNLAWVDSD
QLLYQHFWCLPVIKKKVVVEPVGPIGFQPETFRKFLALYLHGA
Ligand information
>7nqh Chain BA (length=1544) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaauaacuua
acauggacuagcaauuucgguuggggugaccucggaguacaaaaaacccu
ccgagugauuuuaaucuagacaaaccagucaaaauaaccauaacaucacu
uauugauccaaaauuuugaucaacggaacaaguuacccuagggauaacag
cgcaauccuguucuagaguuccuaucgacaauaggguuuacgaccucgau
guuggaucaggacacccaaauggugcaaccgcuauuaaagguucguuugu
ucaacgauuaaaguccuacgugaucugaguucagaccggagcaauccagg
ucgguuucuaucuauuauaaauuucucccaguacgaaaggacaagagaaa
ugggaccaaccucacaaacgcgucucagagauaauuaaugauuuaaucuu
aaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<.....<<<<<....................................
...<......>.................<<.....>>.............
.>>.>>>............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>...>
..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<<..>>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<.>>>>>>.
...>>>>.>>>.>>>>..<<<<.....>>>><<<<<<...........>>
>>>>.<<<<....<<...<<<......>>>...>>.........>>>>..
........<<<....>>>............>>>>..>>>>>>.......<
<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>......
.<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<...
..>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>>>>.<<.<<<<<<<.................>>>>>>
><<<<<...<.........>.>>>>>.<<<...<<<<.<...........
.>..>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nqh Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
Y31 E32 W33 V35 R36 S37 P41 P44 F66 R72 P85 K86 F87 R88 R89 H96 H108 Q109 R110 C111 R112 R173 H223 G264 Q266 L299 R300 P301 R302 R350 Q384 H385 W387 L389 K394 K395
Binding residue
(residue number reindexed from 1)
Y2 E3 W4 V6 R7 S8 P12 P15 F37 R43 P56 K57 F58 R59 R60 H67 H79 Q80 R81 C82 R83 R144 H194 G235 Q237 L270 R271 P272 R273 R321 Q355 H356 W358 L360 K365 K366
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7nqh, PDBe:7nqh, PDBj:7nqh
PDBsum7nqh
PubMed33878294
UniProtA0A287BIV6

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