Structure of PDB 6gb2 Chain Ba Binding Site BS01

Receptor Information
>6gb2 Chain Ba (length=393) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYEWGVRSTRKPEPPPLDRVYEIPGLEPITYAGKMHFMPGLARPVFPPWD
PGWTHPKFRRLPPLHEHPLYKDQACYVFHQRCRLLEGVKQALWLTKTQLI
EGLPEKVLRLADDPRNHIENQDERVLNAISHARLWHSTEDIPKRETYCPV
IVDSLIQLCKSQILKHPSLARRICAQNNTLSATWNRESILLQVHGSSGAR
LNAKDPLPPVASQEEVEATKNHVLETFYPISPTMGLQECNVYDVNDDTGF
QEGYPYPCPHTLYFLESANLRPRRFQPDQLRAKMILFAFGSALAQARLLY
GNDSKVLEQPVVVQSVGTDGRLFQFLVLQLNTTDLASDEGVKNLAWVDSD
QLLYQHFWCLPVIKKKVVVEPVGPIGFQPETFRKFLALYLHGA
Ligand information
>6gb2 Chain BA (length=1549) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacua
acuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaa
acccuccgagugauuuuaaucuagacaaaccagucaaaauaaccauaaca
ucacuuauugauccaaaauuuugaucaacggaacaaguuacccuagggau
aacagcgcaauccuguucuagaguuccuaucgacaauaggguuuacgacc
ucgauguuggaucaggacacccaaauggugcaaccgcuauuaaagguucg
uuuguucaacgauuaaaguccuacgugaucugaguucagaccggagcaau
ccaggucgguuucuaucuauuauaaauuucucccaguacgaaaggacaag
agaaaugggaccaaccucacaaacgcgucucagagauaauuaaugauuua
aucuuaaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<......<<<<....................................
...<......>.................<<.....>>.............
.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<...<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>....
..>.>>..<<<<<.....<<<<....>>>>...<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>......<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<<..>>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<......>>
>>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<........
...>>>>>>.<<<<....<<...<<<......>>>...>>.........>
>>>..........<<<....>>>............>>>>..>>>>>>...
....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.
......<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<
<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>
>>.>>>>....>>..>>>>>>.<<.<<<<<<<.................>
>>>>>><<<<<...<.........>.>>>>>.<<<...<<<<.<......
......>..>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gb2 Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Y31 E32 W33 V35 R36 S37 P44 F66 W78 P85 K86 F87 R88 R89 L90 H96 H108 R110 C111 R112 I170 H223 G264 Q266 L299 R300 R302 Q305 R350 Q384 H385 W387 C388 L389 K395
Binding residue
(residue number reindexed from 1)		Y2 E3 W4 V6 R7 S8 P15 F37 W49 P56 K57 F58 R59 R60 L61 H67 H79 R81 C82 R83 I141 H194 G235 Q237 L270 R271 R273 Q276 R321 Q355 H356 W358 C359 L360 K366
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gb2, PDBe:6gb2, PDBj:6gb2
PDBsum6gb2
PubMed30089917
UniProtA0A287BIV6

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