Structure of PDB 6s47 Chain BZ Binding Site BS01

Receptor Information

>6s47 Chain BZ (length=134) Species: 4932 (Saccharomyces cerevisiae)

SDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAE
KDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVE
KASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD

Ligand information

>6s47 Chain BA (length=1707)

uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccaacggggccuuuccuucuggccaggacuuuuacuuugaaaaaauua
gaguguucaaagcaggcguauugcucgaauauauuagcauggaauaauag
aauaggacguuugguucuauuuuguugguuucuaggaccaucguaaugau
uaauagggacggucgggggcaucaguauucaauugucagaggugaaauuc
uuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguuu
ucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccguc
guagucuuaaccauaaacuaugccgacuagggaucgggugguguuuuuuu
aaugacccacucggcaccuuacgagaaaucaaagucuuuggguucugggg
ggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcuuaauuugacucaacacggggaaacucacc
agguccagacacaauaaggauugacagauugagagcucuuucuugauuuu
gugggugguggugcauggccguucuuaguugguggagugauuugucugcu
uaauugcgauaacgaacgagaccuuaaccuacuaaauaguggugcuagca
uuugcugguuauccacuucuuagagggacuaucgguuucaagccgaugga
aguuugaggcaauaacaggucugugaugcccuuagacguucugggccgca
cgcgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucu
ugguaaucuugugaaacuccgucgugcuggggauagagcauuguaauuau
ugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguug
auuacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaa
uggcuuagugaggccucaggaucugggagaauuuggacaaacuuggucau
uuagaggaacuaaaagucguaacaagguuuccguaggugaaccugcggaa
ggaucau

...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>>[...((((((......<<<<<<<<<<......>>....<<......>
>)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}
}}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.......
...>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<
.....>>>..>>>...............<<.<<....<..........>.
...>>..>>......<<..<...........>..>>.........<<<<<
((....<.<<<<.....<<..))>>.......>>>>>>>>>>..))))))
]]]].........[[[{{.......{{...[[[.[[....<<<<<<.<<<
<..>>>>.>>>>>>....<<<<<..>>>>>...<<<<<.<<.......<<
...<.......>..<<<.....>>>....>>......>>.>>..>>>...
.......[[..((((((((....>>>>>>>>.)))))))).]]......]
]....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>
......>.>>>>>>..>>.......<<....>>...>>>>...>>>>>.>
>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>>>>
...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<<....
.>.>>>>>>>>>>>..>>>...<<..}}>>...>>.....>>>.]]].<<
<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<..<
<.<<<<<<..<<<.<<<<<<......<<........>>..........<<
<<<.<....<<<<<........<<.<<<........>>>.>>......>>
>>>...<<.<<<..<<.<<<<<<....<<<.<<.<......>....<<<.
.....>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<.
...>>>>>>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>...
....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>.
>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....>>>>.
.>>....>>.......>>>>>>>......<....<<<<<<..........
>>>>>>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>.
.....>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<
<<<<<.<<<..<.<<..<...<<<.>>>...>..>>.>..>>>.>>>>>>
>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>
.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6s47 A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
• Resolution: 3.28 Å
• Binding residue (original residue number in PDB): R8 T9 R10 K11 V12 K21 A33 N34 K37 V47 Y48 G59 R61 T62 Q63 F64 G65 Y89 R93 R105 R108 K109 Q110 K112 N113 K116 K117 F119 G120 T121 R124 K128 R131
• Binding residue (residue number reindexed from 1): R7 T8 R9 K10 V11 K20 A32 N33 K36 V46 Y47 G58 R60 T61 Q62 F63 G64 Y88 R92 R104 R107 K108 Q109 K111 N112 K115 K116 F118 G119 T120 R123 K127 R130

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6s47, PDBe:6s47, PDBj:6s47
• PDBsum: 6s47
• PubMed: 31299085
• UniProt: P0CX31|RS24A_YEAST Small ribosomal subunit protein eS24A (Gene Name=RPS24A)