Structure of PDB 7am2 Chain BW Binding Site BS01

Receptor Information
>7am2 Chain BW (length=447) Species: 5689 (Leishmania tarentolae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPARTAQSPLLAKPVKTKVVDNFADMLVTPALQEALADMGVSTPSPIQQT
AIEAVLQRKNTVIAAPHGEGKTLAYLLPLYQNMEKDRDVYKIPLRERRPR
MILLAPTKELVEQLQTVCARLDAATGLTSVCFTSRKRSKYHLSRMLKNTM
ADVLVMDPKLILRLLRTRRLFIEDLRYFAVDEADAMMSSLHDHDAVQLLM
KVQKRNQFKYLWPVQTQYVFVTAYMTRKLEYIVGRKISDPVTCMFRQLMH
RPQARLRHRFYAIRREPEKFTVLMHLLRKNGHVPLPFAEGRRTIIFFRNI
DATTAVFHQLRSAGFAVSLLHASLPYKVRKEMYADFASGRTNILCATDVA
ARGLDLHVDMVINFDVPTNALAYLSRSGRTARMGREGQVLNLYNKHQGVI
VSAIKAFLKDNLPMEGLTNRKADMMQPRYAEWRTHKINALARSYVSL
Ligand information
>7am2 Chain 1 (length=797) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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........<<....>.>..............<<....<<<<<<<.....<
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...........<<.............<<<<<...>>>>>.....<<<<<<
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Receptor-Ligand Complex Structure
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PDB7am2 Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
P106 V107 T109 K110 P198 T199 K200 S226 R227 R229 S230 D249 K251 L252 R258 S281 L282 H283 D284 H285 Q289 M292 K320 Y323 I324 R327 K328 R338 R514 N515 I516 A538 T563 V565 K611 H612 A638 D639 M640 E647 W648 R649 T650 N654 A655 L656
Binding residue
(residue number reindexed from 1)
P14 V15 T17 K18 P106 T107 K108 S134 R135 R137 S138 D157 K159 L160 R166 S189 L190 H191 D192 H193 Q197 M200 K228 Y231 I232 R235 K236 R246 R298 N299 I300 A322 T347 V349 K395 H396 A422 D423 M424 E431 W432 R433 T434 N438 A439 L440
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:1902775 mitochondrial large ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7am2, PDBe:7am2, PDBj:7am2
PDBsum7am2
PubMed33168716
UniProtQ4QHU1

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