Structure of PDB 4v5o Chain BW Binding Site BS01

Receptor Information
>4v5o Chain BW (length=259) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARGPKKHLKRINAPKSWMLNKLGGIWATRPSQGPHKLRESLPLSVLLKER
LNYALNGRDVTLILNDKEQNVFVDGKVRRDKGYPTGLMDVVRIEKTDQSF
RILYDTKGRFVLKSLSKEEAKYKLLKVTAKAIGPNQIPYIVTHDSRTIRF
PNPEIKIGDTLKYDLVNNKIENFAHLESGNVCYIQQGNNIGRVGIIQHIE
KHQGSFDICHVKDAKGNAFATRLGNIFVLGQGKKSWIELPSGDGVRETIL
EERKRKFSY
Ligand information
>4v5o Chain BA (length=1745) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcaaacuaaaaucggcguuc
gacuuagggaguaaacauuuuacugugaaaaaauuagaguguuccaggca
gguuuuagcccgaauacauuagcauggaauaauggaauaggacuaagucc
auuuuauugguucuuggauuugguaaugauuaauagggacaguugggggc
auuaguauuuaauagucagaggugaaauucuuggauuuauuaaggacuaa
cuaaugcgaaagcauuugccaaagauguuuucauuaaucaagaacgaaag
uuaggggaucaaagacgaucagauaccgucguagucuuaacuauaaacua
uaccgacucgggaucggcuggaauaaauguccagucggcaccguaugaga
aaucaaagucuuuggguucugggggaaguaugguacgcaagucugaaacu
uaaaggaauugacggaacagcacaccagaaguggaaccugcggcuuaauu
ugacucaacacggggaaacucacgagcgcaagacagagaagggauugaca
gauugagagcucuuucuugauucuuugggugguggugcauggccguucuu
aguugguggagugauuugucugguuaauuccguuaacgaacgagaccuua
accugcuaacuagucugcuuguaaauaacagguuguacuucuuagaggga
cuauugugcaauaagccaauggaaguuuaaggcaauaacaggucugugau
gccccuagacgugcucggccgcacgcgcguuacaaugacuggcgcaaaaa
guauuuccuguccugggaagguacggguaaucuuauuaauaccagucgug
uuagggauaguucuuuggaauuguggaucuugaacgaggaauuucuagua
agugcaagucaucagcuugcguugauuaugucccugccguuuguacacac
cgcccgucgcuuguaguaacgaauggucuggugaaccuucuggacugcga
cagcaauguugcggaaaaauaaguaaacccuaccauuuggaacaacaaga
agucguaacaagguaucuguaggugaaccugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<<..<<........>>..>>>.>>......<<......
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<<
<.<<<<<........(((((((<<<......>>>.....<......>..>
>>>>.>>..>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<.<<<<<<....>>>>>>..>>>.>
>>......<...<<.........>>...>.........<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<....>>>.>>>>>.>>>>>>>....<<<<....<<<<..<<<<...>>
>>.>>>>....>>>>...<<..<..........<................
<.......>......>.........>....>>.........<<<<<<<<<
<....)))))))..>>>>>>>>>>.....>>....<<<<<<.<<...<<<
<..<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>..
.....<<....>>...>>>>...>>>>>.>>>...>>>...>>.>...<<
<<<<<<...<...<<<<.........>>>>...>>>>>>>>>........
.<<<.<<.<<<..<<<<<<<<<.......>>>>>>>>>..>>>...<<..
]]>>...>>.....>>>.>>>.<<<......<<.<<....>>>>....>>
>..]]]].}<<<<<.<<<.<<<.<<.<<<<<<..<<<.<<<<<<......
<<........>>..........<<<<<<<....<<<<<<.......<<.<
<<........>>>.>>.....>>>>>>...<<.<<<..<<<<<<<<<...
.<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<
.<<..<<<<..<<<<.<<<<<<.....>>>>>>.>.>>>..>>>>.>>..
..<<<<..........>>>>.......>>>>>....>>>.>>>...>.>>
>>>>>.....>>>>>>>...>>.>>>>.>>>.....<<<<<<.......<
<.....<<<<<<<<....>>>.>>>>>....>>........>>>>>>...
...<....<<.<<<..........>>>.>>....>.....>>>>>>....
<<<<<<<<.......>>>>>>>>......>>...>>>.>>>>>>.>>...
.<..<<.<.<<<<<.....<<<<<<<<..<<<..<<.<..<...<<<<<<
<<....>>>>>>>>...>..>.>>..>>>..>>>>>>>>.....>>>>>.
.>.>>...>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v5o Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1.
Resolution3.93 Å
Binding residue
(original residue number in PDB)
R3 G4 P5 K7 H8 K10 R11 I12 M19 K22 L23 I26 W27 A28 T29 R30 Q33 G34 K37 L38 N57 G58 N66 D67 K68 R79 K108 R110 K131 I133 G134 N136 Q137 S146 T148 R150 K157 I158 N189 H199 Q204 A221 R223 I250 K257
Binding residue
(residue number reindexed from 1)
R2 G3 P4 K6 H7 K9 R10 I11 M18 K21 L22 I25 W26 A27 T28 R29 Q32 G33 K36 L37 N56 G57 N65 D66 K67 R78 K107 R109 K130 I132 G133 N135 Q136 S145 T147 R149 K156 I157 N188 H198 Q203 A220 R222 I249 K256
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v5o, PDBe:4v5o, PDBj:4v5o
PDBsum4v5o
PubMed21205638
UniProtP0C233|RS4_TETTH Small ribosomal subunit protein eS4

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