Structure of PDB 8oin Chain BT Binding Site BS01

Receptor Information
>8oin Chain BT (length=288) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPRALDLLRALPRVSLANLKPNPGSRKPERRPRGRRRGRKCGRGHKGERQ
RGTRPRLGFEGGQTPFYLRIPKYGFNEGHSFRHQYQPLSLNRLQYLIDLG
RVDPTQPIDLTQLVNGRGVTIQPSKRDYGVQLVEEGADTFKAKVNIEVQM
ASELAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPE
ALVPYYTDAKNRGYLADPARFPEARLELARKYGYVLPDITKDELFKMLST
RKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYSS
Ligand information
>8oin Chain B8 (length=1571) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacuc
aaccacaaagggauaaaacauaacuuaacauggacuagcaauuucgguug
gggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagacaa
accagucaaaauaaccauaacaucacuuauugauccaaaauuuugaucaa
cggaacaaguuacccuagggauaacagcgcaauccuguucuagaguuccu
aucgacaauaggguuuacgaccucgauguuggaucaggacacccaaaugg
ugcaaccgcuauuaaagguucguuuguucaacgauuaaaguccuacguga
ucugaguucagaccggagcaauccaggucgguuucuaucuauuauaaauu
ucucccaguacgaaaggacaagagaaaugggaccaaccucacaaacgcgu
cucagagauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaau
ccagcccuagaacagggcaca
<<.<......<<<<....................................
...<......>.................<<.....>>.............
.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>...>
..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<....>>><<<..<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>.....>>>..<<<<....<<<<<<<.<
<.........<.....<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>...>..>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<........
....................>>>>>>....>>>>.>>>.>>>>..<<<<.
....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<..
....>>>...>>.........>>>>..........<<<....>>>.....
.......>>>>..>>>>>>.......<<<..<.<<<<<<...<<......
.>>...>>>>>>...>.>>.>.......<.<<<.<<<<<<..<<.<<<<<
<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...
>>>..>....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<
<<<<.................>>>>>>><<<<<...<.........>.>>
>>>.<<<...<<<<.<............>..>>>>...>>>.>>......
...<<<<.......>>>>...
Receptor-Ligand Complex Structure
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PDB8oin Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
A25 L27 N30 G32 S33 R34 K35 E37 R38 R39 P40 R41 G42 R44 R45 G46 R47 K48 C49 G50 R51 H53 K54 G55 E56 R57 Q58 R59 T61 R62 P63 R64 F67 E68 G69 G70 Q71 T72 Y75 L76 R77 K80 S88 R100 R109 T128 Q130 S132 K133 R196
Binding residue
(residue number reindexed from 1)
A17 L19 N22 G24 S25 R26 K27 E29 R30 R31 P32 R33 G34 R36 R37 G38 R39 K40 C41 G42 R43 H45 K46 G47 E48 R49 Q50 R51 T53 R54 P55 R56 F59 E60 G61 G62 Q63 T64 Y67 L68 R69 K72 S80 R92 R101 T120 Q122 S124 K125 R188
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:1990830 cellular response to leukemia inhibitory factor
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8oin, PDBe:8oin, PDBj:8oin
PDBsum8oin
PubMed37141370
UniProtA0A8D0HMG9

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