Structure of PDB 6skf Chain BT Binding Site BS01

Receptor Information
>6skf Chain BT (length=74) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKVFRVKGTFERLGKKQPFTKEYRALKEEHVRELVYSDIGSKHRVPRTK
IWIESIEEIKPEEAEDPVVRRLSL
Ligand information
>6skf Chain BA (length=2929) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccgguggcaacuaagccgccugguggauggcucggcucggggcgccgac
gaagggcguggcaagcugcgauaagccccggcgaggcgcaggcagccguc
gaaccggggaugcccgaaugggaccucccgcggcuugccgcacucccagu
cgggagggggaacgcggggaauugaaacaucuuaguacccgcaggaaaag
aaagcaaaagcgaugccguuaguaggggcgaccgaaagcggcacagggca
aacugaaccccgggccgaaagguucgggggaugugguguuguagggcccg
cggaggagcccugggggcgaagccgaaguccgcuggaacgcggcgccgga
gagggugaaagccccguaggcguaagcccccgagcuccugcggugucccu
gaguaccgucggucggauauccggcgggaagcugggaggcaucggcuccc
aacccuaaauacgucccgagaccgauagcgaacuaguaccgugagggaaa
gcugaaaagcaccccgggaggggggugaaaagagccugaagccaggcggc
gauaggagggugcggcccgaaaggguugacccuccccgaaggaaacacgg
gcgaccguggaguacgaggggaggugaccgggguugcaccguccgucuug
gaucacggggcagggaguucacccgagcggcgagguuaagggggucaacc
ccgaagccgcagggaaaccgacagguccgcagcccguagggcgagggacg
gggugugaaagcgcccggagucgcucgggugagacccgaagccggucgau
cuagcccggggcagggugaagucccucaacagagggauggaggcccgcua
ggggugcugacgugcaauucgcucccgugaccccgggcuaggggugaaag
gccaaucgaggccggcgauagcugguucccgccgaauuaucccccaggau
agcccggccggagguaggcagugggguagagcacugauuggggguuuagg
gggcgaaagccuccggcucccugucaaacuccgaacccacugccgccgua
gauggccggaguaggggggcgguguaagccgucacccgagaggggaacaa
cccagaccgggguuaaggccccaaagugccggcuaaguguuacuccaaag
ggugucccuggccuuagacagcggcccgucgaggucaggggccccgaaaa
uggacggggcuuaagccggccgccgagaccccggcgcacggaccgauugg
uccgugaucggguaggcgggcgugccgauggggcggaagccgggccguga
gguccgguggacccgucgguauugcggauccugccgggaguagcagcaua
gccgggugagaaucccggccgccguaggggccaggguuccacggcaaugu
ucgucagccguggguuagucgguccuaacccgacccguaacucggcgucg
gggaaagggaaacggguuuauauucccguaccgcggugguaggugcggca
acgcaagcccgaggggugacgccucgggguaggcggaccgguccacaagg
ccggcuaagcguauaagcccggggagugccguaauggcgagaaccgggug
aaagcgcgaauggccucccguaagggggguuccgccgaucccuggggccc
gugaaaagccccucgggaacgauccaccgcgaccguaccgagaaccgaca
cuggugccccugggugagaagccuaaggcgugucgggggaaacccagccg
agggaacucggcaaauuggccccguaacuucgggagaaggggugccugcg
gguguguaacccgcaggucgcagugacuaggggggcccgacuguuuagua
aaaacacaggucccagcuagcccgaaaggguuuguacuggggccgacgcc
ugcccagugccgguaugugaagcccggguacaaccgggugaagcaccggu
aaacggcggggguaacuauaacccucuuaagguagcgaaauuccuugucg
guuaaaugccgaccugcaugaauggcguaacgagguccccacuguccccg
gcuggggcccggcgaaaccucugccaggcgcauaugccugggaccuccgg
ugggaagcgaagaccccauggagcuuuacugcagccugccguugccguac
ggcggggggugcgcagcguaggcgggaggcgucgaagcccgcccuccggg
gcggguggagccgcccaugagacaccgcccacccucugccguacggcuaa
cccgcggaagcggggacagcgguaggugggcaguuuggcuggggcggcac
acccucgaaaagguaucgagggugcccuaaggucggcucaggcgggucuc
cgccguagagugcaagggcaaaagccggccugacuggacccguaacagag
gcggguccagccgcgaaagcguggccuagcgaaccccugugccuccccgg
ugggggccagggaugacagaaaagcuacccuggggauaacagagucgucu
cgggcgagagcccauaucgaccccgaggcuugcuaccucgcugucggcuc
uucccauccuggcccugcagcaggggccaaggguggggguguucacccau
uaaaggggaacgugagcuggguuuagaccgucgugagacaggucggaugc
uaucuaccggagguguuggccgccugaggggaaggcucccccaguacgag
aggaacagggagccgcggccucuggucuaccgguuguccuacagggcaua
gccgggcagcuacgccgcagccgauaaggccugaaagcaucuaaggccga
agcggcccccgaaaacaggcggccaccgagggcccgggaagaagacccgg
uugauggggcggggauguaagcgggaagggaaaccgacccguucagucug
ccgcucccaacagcccgagugcuaccggg
<<<<<<.<<<.....<<<<<<<<<<.....<<..<<<<<.<<<<<<<...
...<<<<<<.((..((.>>>.....<<<<<<...<<<))..)).>>>...
...>>>>>>...>>>....<<<....>>><<<<<..>>>>>.<<<<<...
.>>>>>.>>....<<<<<.....<......>......>>>>>........
...<<....>>..<<<<<<.....<<.....>>....>>>>>>..<<<..
.<<<...<<<<<<<<<....>>>>>>>>>.....>>>.....<<<<<<<<
<....<<<<..<<<<<<<...<<<.....<<<<......>>>>.((....
..<<<.....))>>>...>>>....>>>>>>>.>>>>..>>>>.>.>>>>
.....<<<<<<<........>>>>>>>......<<<<<.((((((>>>>>
..>>>......>>.>>>>>>.>>...............<<....>>....
>>.........<<<<....>>>>.................>>>>>>>>>>
........<<<<<<<<<<....<<......<<<<<<<...<....<<<<<
....>>>>>.....>..>>>>>>>...>>.>>>>>>>>>>..<<<<....
....>>>><<<<<<....<<<<<<<<<<<<<..<<<...<<<<.....>>
>>...>>>...<<....>>.....<<<<...<<<<...>>>>...>>>>.
<<<<<<....>>>>>>...>>>>>>>>>>>>>..<<.<..<<<<<<<...
..<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>....
<<<..<<.<<........>>>>.>>>....>>>>>>>>>...<<<.....
>>>......>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>
><<<<<<<<<..<<<.<<<<<<<<<....<<...<<<<.<<<<<<.....
.<.........>...>>>>>>.>>>>..>>.....>>>>>>>>>>>>...
..>>>>>>>.>>..<<<<<<<<<....>>>>>>.>>>....<<<......
>>>...<<<<<<<...<<<(((.....<<<<<<.....<<.........<
<<.<<<<<<<<<<......<..<..>..>...>>>>>>>>>>>>>.....
.....)))>>....>>>>>>.>>>...>>>>>>><<<<<<<<<<....>>
>>>>>>..>>....>>>>>><.<<<<<<<<<<......<<<<<<<<....
>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<......
<<<<<<.......>>>>>><<<<....<<<...<<...<<<<<<...<<.
....>>.>>>>>>....((<<<<<<...<<<<<<<<<.....>>>.>>>>
>>....>>...<<<<<........>>>>>))<<<<<<<<.....<<<...
.>>>...<<<<<<<<<<...<<<<<<<<<..<<<<<<<<<<<<....[>>
>>>>....<<<<.<..<<<<<<.....<<<<...>>>>.....>>>>>>.
..>>>>>.....<<<<<<......>>>>>>>>>>>>...>>>>>>>>>..
.......>>>>>>>>>>......>>>>>>>>>>>>..>>.....<<....
..>>...>>>.<<<<.....>>>>..>>>>...<<<<.....<<<<<<<<
.<<.........<.....<<<<<.....<..>......>>>>><<<<<<<
<<<.....>>>>>>>>>>............<<<<<<<<<..<<<......
...>>>..<<<<<<<....<<<<....>>>>......>>>>>>>.<<<<<
.<<<..<<<<<<<..<<<...<<<<<<......>>>>>>...>>>>>>>>
..>>>>><<<<<<.......>>>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>....>>....<<<<<........>>>>>..<<<<<<<
<.<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<<<<<
<<<<...<<...........<<<<<..<<<......<<<<<.<<<...>>
>>>>>>...>>>............>>>>>..>>...>>>>>>>>>>>...
<<<<<....>>>>>....>>>>>>>>>..>>>>>...<<<.....>>>..
<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<..>>
>>>>.....<<...(((>>....>>>>>>>...<<<<<<<<<<.......
>>>>>>>>>>.<<<....>>>.>>))).......<<<<<.<<<<<.))))
))>>>>>>>>>>..........>>>>..>>>>>>.......<<<<.<.<<
<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<<.<
<<<<<..<<<<<<<<<......>>>>>>..>>>..<<<.......>>>..
....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....>>
..>>>>>>>>>>>....<<<<<<<<..<<<<..<<<<<<<..........
.......>>>>>>><<<<<...<<<<...<<<<<<<<<<]...>>>>>..
>>>>>...>>>>.>>>>>.<<<<.<..<<<<<...........>>>>>..
.>>>>>>>>>>......>>>>>>>.....<<<<<<<<<.......>>>>>
....<<<<<<<<<<<<....<<<<<..<<....>>..>>>>>...>>>>.
>>>>>.>>>...>>>>...>>>.>>>>>>
Receptor-Ligand Complex Structure
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PDB6skf Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Resolution2.95 Å
Binding residue
(original residue number in PDB)
R14 Q19 P20 K23 G42 S43 K44 H45 R46 R49
Binding residue
(residue number reindexed from 1)
R13 Q18 P19 K22 G41 S42 K43 H44 R45 R48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6skf, PDBe:6skf, PDBj:6skf
PDBsum6skf
PubMed32555463
UniProtQ5JGT3|RL18A_THEKO Large ribosomal subunit protein eL20 (Gene Name=rpl18a)

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