Structure of PDB 4v8i Chain BT Binding Site BS01

Receptor Information
>4v8i Chain BT (length=131) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAA
Ligand information
>4v8i Chain AA (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcggguccguggucagcggcggacggguga
guaacgcgugggugaccuacccggaagagggggacaacccggggaaacuc
gggcuaaucccccauguggacccgccccuugggguguguccaaagggcuu
ugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaau
ggcccaccaaggcgacgacggguagccggucugagaggauggccggccac
aggggcacugagacacgggccccacucgaggcagcaguuaggaaucuucc
gcaaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccu
ucgggguguaaacuccugaacccgggacgaaacccccgacgaggggacug
acgguaccgggguaauagcgccggccaacuccgugccagcagccgcggua
auacggagggcgcgagcguuacccggauucacugggcguaaagggcgugu
aggcggccuggggcgucccaugugaaagaccacggcucaaccguggggga
gcgugggauacgcucaggcuagacggugggagagggugguggaauucccg
gaguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggc
agccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaa
ccggauuagauacccggguaguccacgcccuaaacgaugcgcgcuagguc
ucugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugggg
aguacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaa
gcgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccagg
ccuugacaugcuagggaacccgggugaaagccuggggugccccgcgaggg
gagcccuagcacaggugcugcauggccgucgucagcucgugccgugaggu
guuggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcg
guucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggag
gggacgacgucuggucagcauggcccuuacggccugggcgacacacgugc
uacaaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgc
aaaaaggugggcccaguucggauuggggucugcaacccgaccccaugaag
ccggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguucc
cgggccuuguacacaccgcccgucacgccaugggagcgggcucuacccga
agucgccgggagccuacgggcaggcgccgaggguagggcccgugacuggg
gcgaagucguaacaagguagcuguaccggaaggugcggcugga
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<..>>>>>>>>.>>>>>......<<..
.....<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>
>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<..
.>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.....
..>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<.<.........>>>>>>.<<..>>...>>>>>>>........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>....<<<<<......<.<<<<.....>>>>..>.
......>>>>>......<<<<<(((...<<<<<.....<<.)))>>....
...>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<..
.<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....
>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<
<.<..<<<......>>>.....>.>>>>>>>...........<<....>>
.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...
<<<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<
<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<
<<<<<..<<<<<<<<<<......<<........>>..........<<<<<
<<......<<<<<<<<..<<<<<<<....>>>>>>>.....<......>.
...>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>
..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...<<
<.....>>>>.....>>>>>>>.....<<<<<....>>>>>........>
>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>
>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>
.....>>>>>>>......<....<<<<<<<........>>>>>>>....>
.....>>>>>>....<<<<<<<..........>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<..
.<.<<<<.....<<....>>..>>>>.>..>>>>>>>>>>>>>..>>>.>
>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
Receptor-Ligand Complex Structure
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PDB4v8i How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S106 R108 R111 R118 D122
Binding residue
(residue number reindexed from 1)		S106 R108 R111 R118 D122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v8i, PDBe:4v8i, PDBj:4v8i
PDBsum4v8i
PubMed22605777
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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