Structure of PDB 4v65 Chain BT Binding Site BS01

Receptor Information
>4v65 Chain BT (length=56) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRG
RKVIAK
Ligand information
>4v65 Chain BB (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcccagaca
gccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagc
ucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugc
accgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguuc
uguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagug
cgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccgg
aagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccc
cuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccu
guacuugguguuacugcgaaggggggacggagaaggcuauguuggccggg
cgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccg
gaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaac
aaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaauc
guaccccaaaccgacacagguggucagguagagaauaccaaggcgcuuga
gagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggaga
aggcacgcugauauguaggugaggucccucgcggauggagcugaaaucag
ucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugc
aaacacgaaaguggacguauacggugugacgccugcccggugccggaagg
uuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaa
acggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggg
uaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacc
cgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggc
aagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauug
agccuugauguguaggauaggugggaggcuuugaaguguggacgccaguc
ugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaac
guugacccguaauccggguugcggacagugucugguggguaguuugacug
gggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauc
cuggucggacaucaggagguuagugcaauggcauaagccagcuugacugc
gagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugg
uucugaauggaagggccaucgcucaacggauaaaagguacuccggggaua
acaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccu
cgaugucggcucaucacauccuggggcugaaguaggucccaaggguaugg
cuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugaga
caguucggucccuaucugccgugggcgcuggagaacugaggggggcugcu
ccuaguacgagaggaccggaguggacgcaucacugguguucggguuguca
ugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaa
gcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaa
ggguccugaaggaacguugaagacgacgacguugauaggccgggugugua
agcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaa
ccu
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...<<<...................<<<<<....<<<.......>>>...
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<<<<<<<<.........>>>>>>>>>.>>...<<<<.<............
........>>>>..>........<<....>>...<<<<<...........
.......>>>>>...<<<..<<<<......<<<<<<<<<<<<<.<.....
.<<<........>>>.........<<<.......>>>.....>>>...>>
>>>>>>>>>...>>>>........<...<<.............>>...>.
......<<<<..(((.>.>>>..>>>......>>.>>>>>>>.>>.....
.................................<<<<.....>>>>....
...............>>>>>>.>>.........<<....<<<<......>
>>>....>>...................<<........<<.....<<<.<
<........<<.....>>.........<<....>>..<<<.......>>>
.....>>.>>>.....>>..<<.....<<<...............<...<
<.<...<<<<<<......>>>>>>.>....>>....<.............
........>.......>.........<<.......>>.........>>>.
.......>>..<<<<<.....<..<<....>>..>..<<<<<<<...<<<
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.>>>>..>>..>>.>.....>>>>>>>.>>...>>>>>>>..........
<..<........>..>........................<<<<.<<...
.....(......<<<<<<...........<<..<<<<<..<<......<.
<<<<<.<<<..<<<.........>>>..>>>........<<<......>>
>..>>>>>.>..>>..>>>>>.>>............)......>>>>>>.
.......>>>>>><<<<<<<<<....>>>>>>>>>.....>>>>>....<
<<....<..........<<.<<....>>.>>.......>...>>>.....
.........>>...............<<<<<.......>>>>>.<<<<..
..........<..<<<<<...............>>>>.>.....<<..<.
<...<<<...<<<....>>>...>>>...>.>..<<<<..........>>
>>..<<<<<<<<<<<<<...<<<<....<<<...<<<..<<<<<.<<<<<
....[[....>>>>>.....<<<....<<<<<<<<<<<<.<<.....>>>
>>>>>>>..>>>>....>>>........<<<<<....>>>>>....>>>>
>...>>>....>.>>........>>>>...>>....>>>>>>>>>>>..>
>..>......................<<.........>>..>>>>...<<
.........<<......................<<...............
..>>..<<<<<......<.<...<<<<.....>>>>...>.>....>>>>
>............<<<.<<.........................<<<...
.....................>>>.....<<<<........<<<<<..<<
<........<<<<<<.<<....>>..>>>>>>........>>>>>>>>..
......<<<<<.......>>>>.>......................<...
........>............>>>>.......>>.>>>..........>>
......>>...............<..............>...<<<<....
......<...............<<....<...<<<.<<<<..<<<<<<<<
<<<.<<<............<<<<<..<<.......<<<<<<<......>>
>>>>>....>>............>>>>>...>>>.>>>>>>>>>>>...<
<<.<<<<<.......>>>>>>>>.....>>>>.>>>....>.....<<..
.....>>..<<<<<...........>>>>>........<<<<<......<
<<<.........>>>>............((........>>>>>...<<<<
..<<<<....>>>>..>>>>..............)).........<<<<<
<.<<...)))..>>>>>>>>..............>>..............
....<......<<<<<...<<.......>>...>>>>>.......>....
...................<<<..<<.<......>..>>...>>>..<<.
........>>...........................<<..<<......>
>...>>....>..........>>>>....<<<<<<<...<<<<...<<<<
<<...............>>>>>.>..<<<<....<<<.....<<<..<<<
..]]..>>>....>>>.....>>>..>>>>.....<<....<<<<<....
.......>>>>>....>>..>>>>.......>>>>>>>..<<<<<<...>
>>>>>.....<<...<<<.........>>>.....<..<<<<<...<...
.<<<<<....>>>>>...>....>>>>>...>.....>>.....>>>>>>
>>.
Receptor-Ligand Complex Structure
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PDB4v65 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
Resolution9.0 Å
Binding residue
(original residue number in PDB)
A1 V2 Q3 Q4 N5 K6 T8 R9 K11 R12 M14 R15 R16 S17 H18 T25 L27 V29 K36 R39 H41 Y48 K52
Binding residue
(residue number reindexed from 1)
A1 V2 Q3 Q4 N5 K6 T8 R9 K11 R12 M14 R15 R16 S17 H18 T25 L27 V29 K36 R39 H41 Y48 K52
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0000302 response to reactive oxygen species
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0009314 response to radiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v65, PDBe:4v65, PDBj:4v65
PDBsum4v65
PubMed
UniProtP0A7N4|RL32_ECOLI Large ribosomal subunit protein bL32 (Gene Name=rpmF)

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