Structure of PDB 4v4w Chain BT Binding Site BS01

Receptor Information

>4v4w Chain BT (length=94) Species: 562 (Escherichia coli)

MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNM
QAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA

Ligand information

>4v4w Chain B9 (length=108)

ggcggccguagcgcgguggucccaccugaccccaugccgaacucagaagu
gaaacgccguagcgccgaugguaguguggggucuccccaugcgagaguag
gaacugcc

<<<<<.....<<<<<<<.....<<<<<<<.............>>>>..>>
>....>>>>>.>>.<<.<<....<<<<<<<<...>>>>>>>>....>>.>
>..>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v4w Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
• Resolution: 15.0 Å
• Binding residue (original residue number in PDB): Q12 R18 Q87
• Binding residue (residue number reindexed from 1): Q12 R18 Q87

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0009314 response to radiation
• GO:0017148 negative regulation of translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v4w, PDBe:4v4w, PDBj:4v4w
• PDBsum: 4v4w
• PubMed: 16713583
• UniProt: P68919|RL25_ECOLI Large ribosomal subunit protein bL25 (Gene Name=rplY)