Structure of PDB 4v65 Chain BS Binding Site BS01

Receptor Information
>4v65 Chain BS (length=70) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRD
VATGGRVDRFNKRFNIPGSK
Ligand information
>4v65 Chain BB (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcccagaca
gccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagc
ucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugc
accgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguuc
uguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagug
cgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccgg
aagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccc
cuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccu
guacuugguguuacugcgaaggggggacggagaaggcuauguuggccggg
cgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccg
gaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaac
aaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaauc
guaccccaaaccgacacagguggucagguagagaauaccaaggcgcuuga
gagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggaga
aggcacgcugauauguaggugaggucccucgcggauggagcugaaaucag
ucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugc
aaacacgaaaguggacguauacggugugacgccugcccggugccggaagg
uuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaa
acggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggg
uaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacc
cgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggc
aagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauug
agccuugauguguaggauaggugggaggcuuugaaguguggacgccaguc
ugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaac
guugacccguaauccggguugcggacagugucugguggguaguuugacug
gggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauc
cuggucggacaucaggagguuagugcaauggcauaagccagcuugacugc
gagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugg
uucugaauggaagggccaucgcucaacggauaaaagguacuccggggaua
acaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccu
cgaugucggcucaucacauccuggggcugaaguaggucccaaggguaugg
cuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugaga
caguucggucccuaucugccgugggcgcuggagaacugaggggggcugcu
ccuaguacgagaggaccggaguggacgcaucacugguguucggguuguca
ugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaa
gcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaa
ggguccugaaggaacguugaagacgacgacguugauaggccgggugugua
agcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaa
ccu
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...<<<...................<<<<<....<<<.......>>>...
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<<<<<<<<.........>>>>>>>>>.>>...<<<<.<............
........>>>>..>........<<....>>...<<<<<...........
.......>>>>>...<<<..<<<<......<<<<<<<<<<<<<.<.....
.<<<........>>>.........<<<.......>>>.....>>>...>>
>>>>>>>>>...>>>>........<...<<.............>>...>.
......<<<<..(((.>.>>>..>>>......>>.>>>>>>>.>>.....
.................................<<<<.....>>>>....
...............>>>>>>.>>.........<<....<<<<......>
>>>....>>...................<<........<<.....<<<.<
<........<<.....>>.........<<....>>..<<<.......>>>
.....>>.>>>.....>>..<<.....<<<...............<...<
<.<...<<<<<<......>>>>>>.>....>>....<.............
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.>>>>..>>..>>.>.....>>>>>>>.>>...>>>>>>>..........
<..<........>..>........................<<<<.<<...
.....(......<<<<<<...........<<..<<<<<..<<......<.
<<<<<.<<<..<<<.........>>>..>>>........<<<......>>
>..>>>>>.>..>>..>>>>>.>>............)......>>>>>>.
.......>>>>>><<<<<<<<<....>>>>>>>>>.....>>>>>....<
<<....<..........<<.<<....>>.>>.......>...>>>.....
.........>>...............<<<<<.......>>>>>.<<<<..
..........<..<<<<<...............>>>>.>.....<<..<.
<...<<<...<<<....>>>...>>>...>.>..<<<<..........>>
>>..<<<<<<<<<<<<<...<<<<....<<<...<<<..<<<<<.<<<<<
....[[....>>>>>.....<<<....<<<<<<<<<<<<.<<.....>>>
>>>>>>>..>>>>....>>>........<<<<<....>>>>>....>>>>
>...>>>....>.>>........>>>>...>>....>>>>>>>>>>>..>
>..>......................<<.........>>..>>>>...<<
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..>>..<<<<<......<.<...<<<<.....>>>>...>.>....>>>>
>............<<<.<<.........................<<<...
.....................>>>.....<<<<........<<<<<..<<
<........<<<<<<.<<....>>..>>>>>>........>>>>>>>>..
......<<<<<.......>>>>.>......................<...
........>............>>>>.......>>.>>>..........>>
......>>...............<..............>...<<<<....
......<...............<<....<...<<<.<<<<..<<<<<<<<
<<<.<<<............<<<<<..<<.......<<<<<<<......>>
>>>>>....>>............>>>>>...>>>.>>>>>>>>>>>...<
<<.<<<<<.......>>>>>>>>.....>>>>.>>>....>.....<<..
.....>>..<<<<<...........>>>>>........<<<<<......<
<<<.........>>>>............((........>>>>>...<<<<
..<<<<....>>>>..>>>>..............)).........<<<<<
<.<<...)))..>>>>>>>>..............>>..............
....<......<<<<<...<<.......>>...>>>>>.......>....
...................<<<..<<.<......>..>>...>>>..<<.
........>>...........................<<..<<......>
>...>>....>..........>>>>....<<<<<<<...<<<<...<<<<
<<...............>>>>>.>..<<<<....<<<.....<<<..<<<
..]]..>>>....>>>.....>>>..>>>>.....<<....<<<<<....
.......>>>>>....>>..>>>>.......>>>>>>>..<<<<<<...>
>>>>>.....<<...<<<.........>>>.....<..<<<<<...<...
.<<<<<....>>>>>...>....>>>>>...>.....>>.....>>>>>>
>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v65 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
Resolution9.0 Å
Binding residue
(original residue number in PDB)		M1 K2 K3 K8 Y9 E11 I12 T13 A14 N20 K23 R25 K39 H41 Q48 R49 T53 R56 K62 R63 K70
Binding residue
(residue number reindexed from 1)		M1 K2 K3 K8 Y9 E11 I12 T13 A14 N20 K23 R25 K39 H41 Q48 R49 T53 R56 K62 R63 K70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006413 translational initiation
GO:1904689 negative regulation of cytoplasmic translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v65, PDBe:4v65, PDBj:4v65
PDBsum4v65
PubMed
UniProtP0A7M9|RL31_ECOLI Large ribosomal subunit protein bL31 (Gene Name=rpmE)

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