Structure of PDB 6yxy Chain BQ Binding Site BS01

Receptor Information
>6yxy Chain BQ (length=218) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RILQYFVPYERDEVNPVVFMDVTVEGDALGRVSVELFHDIVPKTTENFRS
LCTGERGYSQCPLFYKGIPFHRVIPGFIVQGGDILLKDGRGNVSVFGFPF
PDESFEGKAGKHLRGTVAMAHSAPNQNGSQFFFNLARNDHLDGKFVVCGQ
VIDGWEVVDRVAVLSGSSCGTPVSRAWITECGQSSGDKLEDTERALSGER
ALHTMPGKEVLDILSPRY
Ligand information
>6yxy Chain AA (length=903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yxy Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Y71 Q73 P75 K100
Binding residue
(residue number reindexed from 1)		Y58 Q60 P62 K87
Enzymatic activity
Catalytic site (original residue number in PDB) R85 F90 Q93 H134 F145 L154 F158
Catalytic site (residue number reindexed from 1) R72 F77 Q80 H121 F132 L141 F145
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0016018 cyclosporin A binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005762 mitochondrial large ribosomal subunit
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yxy, PDBe:6yxy, PDBj:6yxy
PDBsum6yxy
PubMed32679035
UniProtQ57WF8

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