Structure of PDB 5j4z Chain BO Binding Site BS01

Receptor Information

>5j4z Chain BO (length=227) Species: 9940 (Ovis aries)

MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKL
THTSTMDAQEVETIWTILPAIILIMIALPSLRILYMMDEINNPSLTVKTM
GHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTV
RMLISSEDVLPSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLFYGQCSEIC
GSNHSFMPIVLELVPLKYFEKWSASML

Ligand information

• Ligand ID: CUA
• InChI: InChI=1S/2Cu
• InChIKey: ALKZAGKDWUSJED-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Cu][Cu]
• Formula: Cu2
• Name: DINUCLEAR COPPER ION
• PDB chain: 5j4z Chain BO Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5j4z The architecture of respiratory supercomplexes.
• Resolution: 5.8 Å
• Binding residue (original residue number in PDB): P161 C196 S197 E198
• Binding residue (residue number reindexed from 1): P161 C196 S197 E198
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.9: cytochrome-c oxidase.

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0022900 electron transport chain
• GO:0042773 ATP synthesis coupled electron transport
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0016020 membrane
• GO:0031966 mitochondrial membrane
• GO:0045277 respiratory chain complex IV

External links

• PDB: RCSB:5j4z, PDBe:5j4z, PDBj:5j4z
• PDBsum: 5j4z
• PubMed: 27654913
• UniProt: O78750|COX2_SHEEP Cytochrome c oxidase subunit 2 (Gene Name=MT-CO2)