Structure of PDB 4v9h Chain BO Binding Site BS01

Receptor Information
>4v9h Chain BO (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
Ligand information
>4v9h Chain AA (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
aggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgu
ggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugc
gcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcg
ccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggg
gcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaa
ccuuaccaggccuugacaugcuagggaacccgggugaaagccuggggugc
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccugaagccggaaucgcuaguaaucgcggaucagccaugccgcgguga
auacguucccgggccuuguacacaccgcccgucacgccaugggagcgggc
ucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggccc
gugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcug
gaucaccuccuuuc
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<.........>>>>>>>>.>>>>>.....
.<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<...
...>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<
<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<
.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>
>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<
......<<<<<..>>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........
..<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<
<<...<<...<<<<.........>>>>...>>>>>>>>..........<<
<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>
>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<
<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.....
.....<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>....
.............>>>>>>>>.<<<.<<<..<<<<<<<......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
...<<<..<<<.....>>>>>>....>>>>>>.....<<<<<....>>>>
>........>>>>.......>.>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>............<<<<<<........>>
>>>>..........>>>>>>....<<<<<<<..........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>
>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>.
..............
Receptor-Ligand Complex Structure
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PDB4v9h Elongation factor G bound to the ribosome in an intermediate state of translocation.
Resolution2.857 Å
Binding residue
(original residue number in PDB)
N13 P48 R49 T96 R97 R107 S116
Binding residue
(residue number reindexed from 1)
N13 P48 R49 T96 R97 R107 S116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4v9h, PDBe:4v9h, PDBj:4v9h
PDBsum4v9h
PubMed23812720
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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