Structure of PDB 4v8i Chain BO Binding Site BS01

Receptor Information
>4v8i Chain BO (length=122) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
Ligand information
>4v8i Chain AA (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcggguccguggucagcggcggacggguga
guaacgcgugggugaccuacccggaagagggggacaacccggggaaacuc
gggcuaaucccccauguggacccgccccuugggguguguccaaagggcuu
ugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaau
ggcccaccaaggcgacgacggguagccggucugagaggauggccggccac
aggggcacugagacacgggccccacucgaggcagcaguuaggaaucuucc
gcaaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccu
ucgggguguaaacuccugaacccgggacgaaacccccgacgaggggacug
acgguaccgggguaauagcgccggccaacuccgugccagcagccgcggua
auacggagggcgcgagcguuacccggauucacugggcguaaagggcgugu
aggcggccuggggcgucccaugugaaagaccacggcucaaccguggggga
gcgugggauacgcucaggcuagacggugggagagggugguggaauucccg
gaguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggc
agccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaa
ccggauuagauacccggguaguccacgcccuaaacgaugcgcgcuagguc
ucugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugggg
aguacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaa
gcgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccagg
ccuugacaugcuagggaacccgggugaaagccuggggugccccgcgaggg
gagcccuagcacaggugcugcauggccgucgucagcucgugccgugaggu
guuggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcg
guucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggag
gggacgacgucuggucagcauggcccuuacggccugggcgacacacgugc
uacaaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgc
aaaaaggugggcccaguucggauuggggucugcaacccgaccccaugaag
ccggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguucc
cgggccuuguacacaccgcccgucacgccaugggagcgggcucuacccga
agucgccgggagccuacgggcaggcgccgaggguagggcccgugacuggg
gcgaagucguaacaagguagcuguaccggaaggugcggcugga
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<..>>>>>>>>.>>>>>......<<..
.....<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>
>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<..
.>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.....
..>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<.<.........>>>>>>.<<..>>...>>>>>>>........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>....<<<<<......<.<<<<.....>>>>..>.
......>>>>>......<<<<<(((...<<<<<.....<<.)))>>....
...>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<..
.<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....
>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<
<.<..<<<......>>>.....>.>>>>>>>...........<<....>>
.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...
<<<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<
<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<
<<<<<..<<<<<<<<<<......<<........>>..........<<<<<
<<......<<<<<<<<..<<<<<<<....>>>>>>>.....<......>.
...>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>
..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...<<
<.....>>>>.....>>>>>>>.....<<<<<....>>>>>........>
>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>
>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>
.....>>>>>>>......<....<<<<<<<........>>>>>>>....>
.....>>>>>>....<<<<<<<..........>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<..
.<.<<<<.....<<....>>..>>>>.>..>>>>>>>>>>>>>..>>>.>
>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v8i How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N13 P48 T96 R97 F99
Binding residue
(residue number reindexed from 1)		N13 P48 T96 R97 F99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v8i, PDBe:4v8i, PDBj:4v8i
PDBsum4v8i
PubMed22605777
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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