Structure of PDB 4v8g Chain BO Binding Site BS01

Receptor Information
>4v8g Chain BO (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
Ligand information
>4v8g Chain AA (length=1505) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uguuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccgcggggucuccguggucagcggcggacgg
gugaguaacgcgugggugaccuacccggaagagggggacaacccggggaa
acucgggcuaaucccccauguggacccgccccuugggguguguccaaagg
gcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggg
uaauggcccaccaaggcgacgacggguagccggucugagaggauggccgg
ccacaggggcacugagacacgggccccacuccuacgggaggcagcaguua
ggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggagg
aagaagcccuucgggguguaaacuccugaacccgggacgaaacccccgac
gaggggacugacgguaccgggguaauagcgccggccaacuccgugccagc
agccgcgguaauacggagggcgcgagcguuacccggauucacugggcgua
aagggcguguaggcggccuggggcgucccaugugaaagaccacggcucaa
ccgugggggagcgugggauacgcucaggcuagacggugggagaggguggu
ggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccga
uggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgu
ggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugc
gcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcg
ccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggg
gcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaa
ccuuaccaggccuugacaugcuagggaacccgggugaaagccuggggugc
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggug
aauacguucccgggccuuguacacaccgcccgucacgccaugggagcggg
cucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcc
cgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcu
ggauc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<<..<<.<<<<<<<<<...>>>>>>>>>.>>>>>......
<<.......<<<<<<<<..<<...<<<<<<<.<<<<<...<<<<<<....
..>>>>>.>...>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<
<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.
......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>
>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>>>>
........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<.
.....<<<<....>>>>.....>>>>....<<<<<......<.<<<<...
..>>>>..>.......>>>>>......<<<<<(((...<<<<<.....<<
.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.
....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....
>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<
....<<<<<<<.<..<<<......>>>.....>.>>>>>>>.........
..<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<
<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<
<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>
>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<
<<<<<.<<..<<<<<..<<<<<<<<<<.......<........>......
.....<<<<<<<......<<<<<<<<..<..<<<<....>>>>.>..<..
.<......>...>>>>>>>>>..<..<<<..<<<<<<.......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>>>>
>........>>>>.........>>>...>>>>>>.>....>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>...........<<<<<<<........>>
>>>>>..........>>>>>.....<<<<<<<..........>>>>>>>.
.....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<
<<<<<<<<...<.<<<<.....<<....>>..>>>>.>..>>>>>>>>>>
>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>
.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4v8g How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
P48 R97
Binding residue
(residue number reindexed from 1)
P48 R97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v8g, PDBe:4v8g, PDBj:4v8g
PDBsum4v8g
PubMed22605777
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

[Back to BioLiP]