Structure of PDB 4v65 Chain BM Binding Site BS01

Receptor Information
>4v65 Chain BM (length=99) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKL
FEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGA
Ligand information
>4v65 Chain BB (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcccagaca
gccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagc
ucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugc
accgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguuc
uguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagug
cgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccgg
aagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccc
cuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccu
guacuugguguuacugcgaaggggggacggagaaggcuauguuggccggg
cgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccg
gaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaac
aaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaauc
guaccccaaaccgacacagguggucagguagagaauaccaaggcgcuuga
gagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggaga
aggcacgcugauauguaggugaggucccucgcggauggagcugaaaucag
ucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugc
aaacacgaaaguggacguauacggugugacgccugcccggugccggaagg
uuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaa
acggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggg
uaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacc
cgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggc
aagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauug
agccuugauguguaggauaggugggaggcuuugaaguguggacgccaguc
ugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaac
guugacccguaauccggguugcggacagugucugguggguaguuugacug
gggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauc
cuggucggacaucaggagguuagugcaauggcauaagccagcuugacugc
gagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugg
uucugaauggaagggccaucgcucaacggauaaaagguacuccggggaua
acaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccu
cgaugucggcucaucacauccuggggcugaaguaggucccaaggguaugg
cuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugaga
caguucggucccuaucugccgugggcgcuggagaacugaggggggcugcu
ccuaguacgagaggaccggaguggacgcaucacugguguucggguuguca
ugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaa
gcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaa
ggguccugaaggaacguugaagacgacgacguugauaggccgggugugua
agcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaa
ccu
<<<<<<<<.......<<.<<<<<<..........<<<<<<<<<<<<<...
...<<<...................<<<<<....<<<.......>>>...
.....>>>>>...>>>....<<......>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<.<............
........>>>>..>........<<....>>...<<<<<...........
.......>>>>>...<<<..<<<<......<<<<<<<<<<<<<.<.....
.<<<........>>>.........<<<.......>>>.....>>>...>>
>>>>>>>>>...>>>>........<...<<.............>>...>.
......<<<<..(((.>.>>>..>>>......>>.>>>>>>>.>>.....
.................................<<<<.....>>>>....
...............>>>>>>.>>.........<<....<<<<......>
>>>....>>...................<<........<<.....<<<.<
<........<<.....>>.........<<....>>..<<<.......>>>
.....>>.>>>.....>>..<<.....<<<...............<...<
<.<...<<<<<<......>>>>>>.>....>>....<.............
........>.......>.........<<.......>>.........>>>.
.......>>..<<<<<.....<..<<....>>..>..<<<<<<<...<<<
<<<<<.<....<<<...<<..<<<<...<<<<<<<.....>>>>>.>>..
.>>>>..>>..>>.>.....>>>>>>>.>>...>>>>>>>..........
<..<........>..>........................<<<<.<<...
.....(......<<<<<<...........<<..<<<<<..<<......<.
<<<<<.<<<..<<<.........>>>..>>>........<<<......>>
>..>>>>>.>..>>..>>>>>.>>............)......>>>>>>.
.......>>>>>><<<<<<<<<....>>>>>>>>>.....>>>>>....<
<<....<..........<<.<<....>>.>>.......>...>>>.....
.........>>...............<<<<<.......>>>>>.<<<<..
..........<..<<<<<...............>>>>.>.....<<..<.
<...<<<...<<<....>>>...>>>...>.>..<<<<..........>>
>>..<<<<<<<<<<<<<...<<<<....<<<...<<<..<<<<<.<<<<<
....[[....>>>>>.....<<<....<<<<<<<<<<<<.<<.....>>>
>>>>>>>..>>>>....>>>........<<<<<....>>>>>....>>>>
>...>>>....>.>>........>>>>...>>....>>>>>>>>>>>..>
>..>......................<<.........>>..>>>>...<<
.........<<......................<<...............
..>>..<<<<<......<.<...<<<<.....>>>>...>.>....>>>>
>............<<<.<<.........................<<<...
.....................>>>.....<<<<........<<<<<..<<
<........<<<<<<.<<....>>..>>>>>>........>>>>>>>>..
......<<<<<.......>>>>.>......................<...
........>............>>>>.......>>.>>>..........>>
......>>...............<..............>...<<<<....
......<...............<<....<...<<<.<<<<..<<<<<<<<
<<<.<<<............<<<<<..<<.......<<<<<<<......>>
>>>>>....>>............>>>>>...>>>.>>>>>>>>>>>...<
<<.<<<<<.......>>>>>>>>.....>>>>.>>>....>.....<<..
.....>>..<<<<<...........>>>>>........<<<<<......<
<<<.........>>>>............((........>>>>>...<<<<
..<<<<....>>>>..>>>>..............)).........<<<<<
<.<<...)))..>>>>>>>>..............>>..............
....<......<<<<<...<<.......>>...>>>>>.......>....
...................<<<..<<.<......>..>>...>>>..<<.
........>>...........................<<..<<......>
>...>>....>..........>>>>....<<<<<<<...<<<<...<<<<
<<...............>>>>>.>..<<<<....<<<.....<<<..<<<
..]]..>>>....>>>.....>>>..>>>>.....<<....<<<<<....
.......>>>>>....>>..>>>>.......>>>>>>>..<<<<<<...>
>>>>>.....<<...<<<.........>>>.....<..<<<<<...<...
.<<<<<....>>>>>...>....>>>>>...>.....>>.....>>>>>>
>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v65 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
Resolution9.0 Å
Binding residue
(original residue number in PDB)		M1 I2 E4 E5 R6 K9 R12 H15 S17 K19 T29 K36 D37 K40 K44 N59 L61 V62 V63 K64 G65 K66 K68 R69 H70 R73 G75 R76 R77 S78 W80 K81 K82 Y84
Binding residue
(residue number reindexed from 1)		M1 I2 E4 E5 R6 K9 R12 H15 S17 K19 T29 K36 D37 K40 K44 N59 L61 V62 V63 K64 G65 K66 K68 R69 H70 R73 G75 R76 R77 S78 W80 K81 K82 Y84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v65, PDBe:4v65, PDBj:4v65
PDBsum4v65
PubMed
UniProtP0ADZ0|RL23_ECOLI Large ribosomal subunit protein uL23 (Gene Name=rplW)

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