Structure of PDB 5el6 Chain BI Binding Site BS01

Receptor Information
>5el6 Chain BI (length=97) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRK
AESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLS
Ligand information
>5el6 Chain 13 (length=1496) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccguggucagcggcggacgggugaguaacgc
gugggugaccuacccggaagagggggacaacccggggaaacucgggcuaa
ucccccauguggacccgccccuugggguguguccaaagggcuuugcccgc
uuccggaugggcccgcgucccaucagcuaguuggugggguaauggcccac
caaggcgacgacggguagccggucugagaggauggccggccacaggggca
cugagacacgggccccacuccuacgggaggcagcaguuaggaaucuuccg
caaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccuu
cgggguguaaacuccugaacccgggacgaaacccccgacgaggggacuga
cgguaccgggguaauagcgccggccaacuccgugccagcagccgcgguaa
uacggagggcgcgagcguuacccggauucacugggcguaaagggcgugua
ggcggccuggggcgucccaugugaaagaccacggcucaaccgugggggag
cgugggauacgcucaggcuagacggugggagagggugguggaauucccgg
aguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggca
gccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaac
cggauuagauacccggguaguccacgcccuaaacgaugcgcgcuaggucu
cugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugggga
guacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaag
cgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccaggc
cuugacaugcuagggaacccgggugaaagccuggggugccccgcgagggg
agcccuagcacaggugcugcauggccgucgucagcucgugccgugaggug
uuggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcgg
uucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggagg
ggacgacgucuggucagcauggcccuuacggccugggcgacacacgugcu
acaaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgca
aaaaggugggcccaguucggauuggggucugcaacccgaccccaugaagc
cggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguuccc
gggccuuguacacaccgcccgucacgccaugggagcgggcucuacccgaa
gucgccgggagccuacgggcaggcgccgaggguagggcccgugacugggg
cgaagucguaacaagguagcuguaccggaaggugcggcuggacacc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<<..<<.<........>.>>>>>......<<.......<<
<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>....
.>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>>.>
>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<....>>>>...>>>>>>>........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<..
..>>>>.....>>>>....<<<<<........<<<<.....>>>>.....
.....>>>>>......<<<<<(((...<<<<<.....<<.)))>>.....
..>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<...
<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>
>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<
.<..<<<......>>>.....>.>>>>>>>...........<<....>>.
>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...<
<<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<<
<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<..
....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<
<<<<..<<<<<<<<<<......<<........>>..........<<<<<<
<......<<<<<<<<..<<<<<<<....>>>>>>>....<<......>>.
..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>.
.<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...<<<
.....>>>>.....>>>>>>>.....<<<<<....>>>>>........>>
>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>
.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>.
....>>>>>>>...........<<<<<<<........>>>>>>>......
....>>>>>>....<<<<<<<..........>>>>>>>......>>...>
>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<...
<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>.>>
>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>.......
Receptor-Ligand Complex Structure
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PDB5el6 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		L10 K14 R15 H16 Q18 S19 R22 R23 R25 N26 K27 A28 K29 S31 T35 L36 K39 I55 R57 E60 S61 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 R89 G102 G103 L104 S105
Binding residue
(residue number reindexed from 1)		L2 K6 R7 H8 Q10 S11 R14 R15 R17 N18 K19 A20 K21 S23 T27 L28 K31 I47 R49 E52 S53 K57 K60 S62 K66 A70 R71 K73 S74 R75 M77 R81 G94 G95 L96 S97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5el6, PDBe:5el6, PDBj:5el6
PDBsum5el6
PubMed26791911
UniProtP80380|RS20_THET8 Small ribosomal subunit protein bS20 (Gene Name=rpsT)

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