Structure of PDB 8oiq Chain BH Binding Site BS01

Receptor Information
>8oiq Chain BH (length=110) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPKNRRSIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHILCGYCYE
KVRKETAEIRRQMGKQEGGPFRAPTTETVVLYSGETPSEQDQGKRIIERE
RKRPSWFTQN
Ligand information
>8oiq Chain B8 (length=1571) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacuc
aaccacaaagggauaaaacauaacuuaacauggacuagcaauuucgguug
gggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagacaa
accagucaaaauaaccauaacaucacuuauugauccaaaauuuugaucaa
cggaacaaguuacccuagggauaacagcgcaauccuguucuagaguuccu
aucgacaauaggguuuacgaccucgauguuggaucaggacacccaaaugg
ugcaaccgcuauuaaagguucguuuguucaacgauuaaaguccuacguga
ucugaguucagaccggagcaauccaggucgguuucuaucuauuauaaauu
ucucccaguacgaaaggacaagagaaaugggaccaaccucacaaacgcgu
cucagagauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaau
ccagcccuagaacagggcaca
<<.<......<<<<....................................
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.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>...>
..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
......<<<.........>>>............<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<....>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<.........<.....<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>...>..>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<........
....................>>>>>>....>>>>.>>>.>>>>..<<<<.
....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<..
....>>>...>>.........>>>>..........<<<....>>>.....
.......>>>>..>>>>>>.......<<<..<.<<<<<<...<<......
.>>...>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<
<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...
>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<
<<<<.................>>>>>>><<<<<...<.........>.>>
>>>.<<<...<<<<.<............>..>>>>...>>>.>>......
...<<<<.......>>>>...
Receptor-Ligand Complex Structure
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PDB8oiq Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		A79 A80 P81 K82 N83 R84 R85 S86 I87 V89 N90 R91 C92 R93 R94 R95 N96 P97 Q98 N106 H120 R131 R138 R139 G142 F149
Binding residue
(residue number reindexed from 1)		A1 A2 P3 K4 N5 R6 R7 S8 I9 V11 N12 R13 C14 R15 R16 R17 N18 P19 Q20 N28 H42 R53 R60 R61 G64 F71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8oiq, PDBe:8oiq, PDBj:8oiq
PDBsum8oiq
PubMed37141370
UniProtI3LTC4

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