Structure of PDB 7aih Chain BH Binding Site BS01

Receptor Information
>7aih Chain BH (length=214) Species: 5664 (Leishmania major) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYMPYTPVATNPVVYFDITAEGDALGRVSVELFRDVVPRTSENFRSLCTG
ERGYGQCLLYYKGTPFHRIIPGFVMQGGDILTKDGRSNVSVFGYPFPDES
FEGKAGKHLPGTVGMAHSGPNQNGSQFFFNLGRNEQLDRKFVVVGQVLGG
WEIVNQVVKLCGSRCGTPVSRAWISDCGQSGGYMAEETQEALQGERAQHV
IPGKEVLDLIQPRY
Ligand information
>7aih Chain 1 (length=1087) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB7aih Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y69 Q71 R101 Q213 V215
Binding residue
(residue number reindexed from 1)		Y54 Q56 R86 Q198 V200
Enzymatic activity
Catalytic site (original residue number in PDB) R83 F88 Q91 H132 F143 L152 F156
Catalytic site (residue number reindexed from 1) R68 F73 Q76 H117 F128 L137 F141
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0016018 cyclosporin A binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aih, PDBe:7aih, PDBj:7aih
PDBsum7aih
PubMed33168716
UniProtQ4QBK2

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