Structure of PDB 8oeq Chain BF Binding Site BS01

Receptor Information
>8oeq Chain BF (length=171) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSQNVMRELRIEKLVLNICVGESGDRLTRAAKVLEQLSGQTPVQSKARYT
VRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRSKNFSATGNFG
FGIDEHIDLGIKYDPSIGIYGMDFYVVMGRAGARVTRRKRARSTIGNSHK
TNKEDTIQWFKTRYDAEVLDK
Ligand information
>8oeq Chain AS (length=3199) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauugcggu
uuaccgggccagcaucgguuuggagcggcaggauaauggcggaggaaugu
ggcacggcuucugcuguguguuauagccucugacgauacugccagccuag
accgaggacugcgguuuuuaccuaggauguuggcauaaugaucuuaaguc
gcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuug
gguguaaaacccguacgcguaaugaaagugaacgaaggugggggcccauu
agggugcaccaucgaccgauccugauguguucggauggauuugaguaaga
gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga
agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc
gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua
gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu
uuaugagguaaagcgaaugauuagaagucuugggguugaaaugaccuuaa
cuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauugaac
guggacaauugaaugaagagcuuuuagugggccauuuuugguaagcagaa
cuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaugcacg
cucaucagacaccacaaaagguguuaguucaucuagacagccggacggug
gccgcuaaggaguguguaaacucaccggccgaaugaacuagcccugaaaa
uggauggcgcucaagcgugcuacuuauacuucaccgugauugcuguuuug
acgcuuucacgaguaggcaggcguggaggucagugacgaagccuuugcug
uaaagcugggucgaacggccucuagugcagaucuuggugguaguagcaaa
uauucaaaugagaacuuugaagacugaaguggggaaagguuccaugucaa
cagcaguuggacauggguuagucgauccuaagagauggggaagcuccguu
ucaacgugcuugauuuuucaggccaaccaucgaaagggaauccgguuaaa
auuccggaacuuggauauggauucuucacggcaacguaacugaaugugga
gacgucggcgugagcccugggaggaguuaucuuuucuucuuaacagcuua
ucacccuggaauugguuuauccggagauggggucuuauggcuggaagagc
gcgguaauuuugccgcguccggugcgcuuacgacgguccuugaaaaucca
caggaaggaauaguuuucaugccaagucguacucauaaccgcagcagguc
uccaagguuaacagccucuaguugauagaauaauguagauaagggaaguc
ggcaaaauagauccguaacuucgggauaaggauuggcucuaaggaucggg
cacguuuaacgaucaacuuagaacugguacggacaaggggaaucugacug
ucuaauuaaaacauagcauugugauggucagaaagugauguugacacaau
gugauuucugcccagugcucugaaugucaaagugaagaaauucaaccaag
cgcggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugc
cucgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacu
gucccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggca
gaaucagcggggaaagaagacccuguugagcuugacucuaguuugacauu
gugaaaagacauggaggguguagaauaagugggagcuucggcgccgguga
aauaccacuaccucuauaguuuuuuuacuuauucaaugaagcggagcugg
aggucaaacuccacguucuagcauuaagcccucugggcgauccggguuga
agacauugucagguggggaguuuggcuggggcggcacaucuguuaaacga
uaacgcagguguccuaagggggacucauggagaacagaaaucuccaguag
aacaaaaggguaaaaguccccuugauuuugauuuucagugugaauacaaa
ccaugaaaguguggccuaucgauccuuuagucccucggaauuugaggcua
gaggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagc
guucauagcgacauugcuuuuugauucuucgaugucggcucuuccuauca
uaccgaagcagaauucgguaagcguuggauuguucacccacuaauaggga
acgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacug
augaauguuaucgcaauaguaauugaacuuaguacgagaggaaccguuca
uucagauaauugguuuuugcggcugucugaucaggcaacgccgcgaagcu
accaucugcuggauuauggcugaacgccucuaagucagaauccaugcuag
aacgcgaugauuuuugcccugcacauuuuagauggauacgaauaagacuu
uuuagucgcuggaccauagcaggcuggcaacggugcgcuuagcggaaagg
cuuugugcgcuugccggcggauagcaaugucaacaugcgcggggauaaau
ccuuugcauacgacuuagauguacaacggaguauuguaagcaguagagua
gccuuguuguuacgaucugcugagauuaagcucuuguugucugauuugu
.......................<<<<<<.....<......>......>>
>>>.>.........<<....>>..<<<<<......<<.....>>.....>
>>>>..<<<...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<...<<<<<<<<<<<<.<<<<<<<.....<<<<......>>>
>.(.......<<<......)>>>....>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<.........
...>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<<<<<.....
.<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>>>.>>>>>>
>>>>........<<<....>>>.....>>>>>>>....>>>>>>>>>>>>
..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<..<<
<<<.....>>>>>..>>>...<<....>>.......<<<<<..<<<<...
.>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>....
>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<........>>
>>>>>>....>>>>>>>>>...<<.......>>......>>>>>>...>.
.>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<<.<<
<<<<<.....<<<....<<<....<<<<...<<<<<.......>>>>>.>
>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<......>>>>
>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>
.>>>>....<<<..[...>>>...<<<<<<<..<<<<(((.....<<<<<
<.....<<.....]....<<<.<<<<<<<<<<.......<<<<<.<<<..
.>>>.........<<....>>...>>>>>...>>>>>>>>>>>>>.....
.....))).>>...>>>>>>.>>>>..>>>>>>><<<<<..<<.......
..>>..>>>>>....>>>>>>..<<<<<<<<.<<......<<<<..<<<.
...>>>.>>>>...>>>>>>>>>>........>>>>>><<.....<<...
..<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>...
.......<<<<<<....>>>>>>......>>....>>...<<<<<.....
...>>>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<
...<<<<.<<<<<<<.<<<<<<<<<<..[[[..>>>>>><...<<<<<..
..<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<
<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>
>>..........>>>..>>>>>>>>>>>>..>>.....<<......>>>>
>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<......
...<.....<<<<<.....<..>......>>>>><<.<<<<<<<<<<<..
.........>>>>>..>>>>>>.>>............<<<<<<<<<..<<
<.........>>>..<<<<<<<....<<<<.....>>>>......>>>>>
>>...<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>
>>.>>>>..>>>>><<<<<<.......>>>>>>........<........
...<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>
..>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>..
..<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<..
<<<<<<<<<<<<...<<.................<......>........
............>>.>>.>>>>>>>>>>...<<<<<.....<<<<..<<<
<<......>>>>>..............<<<<...>>>>..>>>>..>>>>
>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>....
.<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>
.<<<....>>>.>>)))......<<<<<<<..<<<<.))))))>>>>>>>
>>>>.........>>>>..>>>>>>.......<<.<...<<<<<<...<<
.......>>...>>>>>>....>.>.>.......<<<<<.<<<<<<..<.
<<<<<<<......>>>>>>>...>.<<<.........>>>.....>>>>>
..>...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>
>>....<<<<<<<<..<<<<.<.<<<<<.................>>>>>
.><<<<<...<<<<....<<<<<<<<<<]]].>>>>>..>>>>>...>>>
>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>.
...>>>>>>>>.....<<<<<<.<<<.<.....<<..........<<<<.
...>>>>......>>.......<<<<<<...<<<<<<<..<<<......>
>>..>>>>>>>.>>>>>>..............>.>>>.>>>>>>..<<<<
<<<.............>>....<<<<<<<<<.<<<....<<<<....<<<
<<......>>>>>...>>>>...>>>....>>>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
K16 N20 C22 S48 A50 R51 Y52 F57 K94 N95 S97 T99 N101 G103 F104 G105 I106 G124 M125 D126 Y128 K142
Binding residue
(residue number reindexed from 1)
K13 N17 C19 S45 A47 R48 Y49 F54 K91 N92 S94 T96 N98 G100 F101 G102 I103 G121 M122 D123 Y125 K139
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