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Receptor Information

>7zuw Chain BD (length=294) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVV
RFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGL
LIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRT
TTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGH
VSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAF
KPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ

>7zuw Chain 4 (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gguugcggccauaucuaccagaaagcaccguuucccguccgaucaacugu
aguuaagcugguaagagccugaccgaguaguguagugggugaccauacgc
gaaacucaggugcugcaaucu

<<<<<<<<<....<<<<<<<<.....<<.<<..............>>...
.>>....>>>>>>.>><<<<<<.......<<<<<..<<....>>.>>>>>
.....>>>>>>>>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7zuw Structural basis for clearing of ribosome collisions by the RQT complex.
Resolution	4.3 Å
Binding residue (original residue number in PDB)	S10 S13 S14 F16 T18 F20 R21 R22 R24 T28 Y30 R33 R50 R54 T56 N57 K58 Q63 I69 T70 G71 D72 V74 G91 N94 W95 R152 T155 A157 R158 Y198 H203 Y207 E210 R218 E221 L222 F223 K224 T256 K258 K259 F260 Q264 Y265 A266 E268 S269 Y272 R273 Q274 T275 K276 L277 K279 R282 R285 K289
Binding residue (residue number reindexed from 1)	S7 S10 S11 F13 T15 F17 R18 R19 R21 T25 Y27 R30 R47 R51 T53 N54 K55 Q60 I66 T67 G68 D69 V71 G88 N91 W92 R149 T152 A154 R155 Y195 H200 Y204 E207 R215 E218 L219 F220 K221 T253 K255 K256 F257 Q261 Y262 A263 E265 S266 Y269 R270 Q271 T272 K273 L274 K276 R279 R282 K286

Enzyme Commision number

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

PDB	RCSB:7zuw, PDBe:7zuw, PDBj:7zuw
PDBsum	7zuw
PubMed	36801861
UniProt	P26321\|RL5_YEAST Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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Structure of PDB 7zuw Chain BD Binding Site BS01