Structure of PDB 7nsh Chain BD Binding Site BS01

Receptor Information
>7nsh Chain BD (length=240) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATSVSWKSRTKYTVMPVKMRKSGGRNHTGQIQVHGIGGGHKQRYRMIDFL
RFRPEHESKPGPFEEKVIAVRYDPCRSADIALVAGGNRKRWIIATENMKA
GDTVLNSDHIGRMAVAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRA
AGTCGVLLRKVNGTAIIQLPSKRQMQVLETCIATVGRVSNVDHNKRVIGK
AGRNRWLGKRPNSGLWQRKGGWAGRKIRPLPPMKSYVKLP
Ligand information
>7nsh Chain BA (length=1544) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaauaacuua
acauggacuagcaauuucgguuggggugaccucggaguacaaaaaacccu
ccgagugauuuuaaucuagacaaaccagucaaaauaaccauaacaucacu
uauugauccaaaauuuugaucaacggaacaaguuacccuagggauaacag
cgcaauccuguucuagaguuccuaucgacaauaggguuuacgaccucgau
guuggaucaggacacccaaauggugcaaccgcuauuaaagguucguuugu
ucaacgauuaaaguccuacgugaucugaguucagaccggagcaauccagg
ucgguuucuaucuauuauaaauuucucccaguacgaaaggacaagagaaa
ugggaccaaccucacaaacgcgucucagagauaauuaaugauuuaaucuu
aaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<.....<<<<<....................................
...<......>...........<.....<<.....>>....>........
.>>.>>>............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>...>
..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<....>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<.>>>>>>.
...>>>>.>>>.>>>>..<<<<.....>>>><<<<<<...........>>
>>>>.<<<<....<<...<<<......>>>...>>.........>>>>..
........<<<....>>>............>>>>..>>>>>>.......<
<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>......
.<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<...
..>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>>>>.<<.<<<<<<<.................>>>>>>
><<<<<...<.........>.>>>>>.<<<...<<<<.............
....>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nsh Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
A61 W66 K67 K71 M75 P76 K78 R80 K81 S82 G84 R85 H87 G89 Q90 I91 Q92 V93 I96 G98 H100 K101 Q102 R103 Y104 R105 F109 R131 Y132 P134 R136 L142 K149 R203 Q206 Y207 I208 R209 A210 A211 G212 T213 L229 P230 S231 R233 H253 N254 I258 G259 K260 A261 G262 R263 N264 R265 W266 R270 P271 N272 S273 G274 L275 W276 Q277 R278 K279 G280 G281 W282 A283 G284 R285 K286 R288 K294 Y296
Binding residue
(residue number reindexed from 1)
A1 W6 K7 K11 M15 P16 K18 R20 K21 S22 G24 R25 H27 G29 Q30 I31 Q32 V33 I36 G38 H40 K41 Q42 R43 Y44 R45 F49 R71 Y72 P74 R76 L82 K89 R143 Q146 Y147 I148 R149 A150 A151 G152 T153 L169 P170 S171 R173 H193 N194 I198 G199 K200 A201 G202 R203 N204 R205 W206 R210 P211 N212 S213 G214 L215 W216 Q217 R218 K219 G220 G221 W222 A223 G224 R225 K226 R228 K234 Y236
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0031090 organelle membrane
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7nsh, PDBe:7nsh, PDBj:7nsh
PDBsum7nsh
PubMed33878294
UniProtF1RRN2

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