Structure of PDB 4v6o Chain BD Binding Site BS01 |
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| >4v6o Chain BB (length=2904)
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gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcccagaca
gccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagc
ucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugc
accgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguuc
uguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagug
cgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccgg
aagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccc
cuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccu
guacuugguguuacugcgaaggggggacggagaaggcuauguuggccggg
cgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccg
gaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaac
aaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaauc
guaccccaaaccgacacagguggucagguagagaauaccaaggcgcuuga
gagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggaga
aggcacgcugauauguaggugaggucccucgcggauggagcugaaaucag
ucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugc
aaacacgaaaguggacguauacggugugacgccugcccggugccggaagg
uuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaa
acggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggg
uaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacc
cgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggc
aagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauug
agccuugauguguaggauaggugggaggcuuugaaguguggacgccaguc
ugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaac
guugacccguaauccggguugcggacagugucugguggguaguuugacug
gggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauc
cuggucggacaucaggagguuagugcaauggcauaagccagcuugacugc
gagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugg
uucugaauggaagggccaucgcucaacggauaaaagguacuccggggaua
acaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccu
cgaugucggcucaucacauccuggggcugaaguaggucccaaggguaugg
cuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugaga
caguucggucccuaucugccgugggcgcuggagaacugaggggggcugcu
ccuaguacgagaggaccggaguggacgcaucacugguguucggguuguca
ugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaa
gcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaa
ggguccugaaggaacguugaagacgacgacguugauaggccgggugugua
agcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaa
ccuu |
<<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[.<<...
...<<.<<<.[..(((.>>>.....<<<<<<<..<<.)))..]..>>...
...>>>>>>>....>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<......
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>...((..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..<<<<>>>>>..))........].>>>>>>>.]].....
..........<<....>>....]].........<<<.......>>>....
.........}....>>>>>>>>>>>.......<<<...<<<<<......>
>>>>...>>>...<............>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<
<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<......
..>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>.
.....>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<.<..<<<
<<<<<<.....<<<...<.<.<<<<...<<.<.<<.....>>.>..>>..
.>>>>.>.>..>>.>.....>>>>>>>.>>...>>>>>>>.>...<<<<<
<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<...
.<<<(((.....<<<<<<...........<<..<<<<<..<<........
<<<<<.<<...<<<<.......>>>>...>>........<<<......>>
>..>>>>>....>>..>>>>>.>>...........))).....>>>>>>.
>>>....>>>>>><<<<<<<<<....>>>>>>>>>....>>>>>>.<<<<
<<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>.>.
.....>>>>>>.......<<.....<<<<<<.......>>>>>><<<<..
..<<<<<.<<...<<<<<....<<.....>>..>>>>>....((<<<.<<
<...<<<...<<<....>>>...>>>...>>>..<<<<<........>>>
>>))<<<<<<<<<<<<<...<<<<.....<<<..<<<..<<<<<<<<<<<
....(((...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>
>>>>>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>
>...>>>...>>>..........>>>>...>>....>>>>>>>>>>>.>>
>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<
<....<<<<<<<<.<<...............<<<<<....<<..>>....
.>>>>><<<<<<.....<<<...<<<<.....>>>>...>>>...>>>>>
>............<<<<<<<<<..<<<.........>>>..<<<<<<<..
...<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<
<<.......<<<<<..<<....>>...>>>>>.....>..>>>>>>>>..
>>>>><<<<<<.......>>>>>>........<...........<<<<<.
......>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>>
>>>>.>>>>>>...........<<<<<........>>>>>..<<<<<<<<
.(((.[[......<<<<...<<<<..<<<<<.<<<.<<<<<.<<<<<<<<
<<<.<<<..............<<<..<........<.<<<<<<....>>>
>>>.>....>.............>>>....>.>>.>>>>>>>>>>>...<
<<.<<<<<.......>>>>>>>>....>>>>>.>>>..>>>>>..<<<<.
....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<
<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<<
..<<<<....>>>>..>>>>.<<<....>>>.>>))).......<<<<<<
<.((..>>>>..))>>>>>>>.............>>>>....>>>>....
...<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>..
.....<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<
<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<
<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<
.)))..>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<....
.......>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<<...>
>>>>>.....<<..<<<<.........>>>>....<<<<<<<<..<<...
.<<<<<....>>>>>...>>...>>>>>.>>>.....>>.....>>>>>>
>>.. |
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| PDB | 4v6o Structural characterization of mRNA-tRNA translocation intermediates. |
| Resolution | 14.7 Å |
Binding residue
(original residue number in PDB) | V3 C5 K6 P7 T8 P10 G11 R12 R13 H14 K17 V18 V19 L23 K25 G26 K27 P28 A30 P31 L33 K35 K38 S39 G40 G41 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 H52 I53 G55 K58 Y61 D71 E81 Y82 D83 P84 N85 R86 S87 L94 K96 D97 G98 E99 R100 M145 K146 P147 G148 K149 G151 Q152 L153 R155 S156 A157 Y170 L175 R176 S177 E179 R181 E184 D186 A197 M200 R202 V203 L204 G205 K206 A207 G208 R211 W212 R213 V215 R216 P217 T218 V219 R220 G221 T222 A223 M224 N225 P226 V227 D228 H229 P230 H231 G232 G233 G234 E235 G236 R237 N238 F239 G240 K241 H242 P243 V244 P246 W247 G248 Q250 T251 K252 G253 K254 K255 T256 R257 S258 N259 K260 R261 T262 D263 K264 F265 I266 R269 R270 S271 K272 |
Binding residue
(residue number reindexed from 1) | V3 C5 K6 P7 T8 P10 G11 R12 R13 H14 K17 V18 V19 L23 K25 G26 K27 P28 A30 P31 L33 K35 K38 S39 G40 G41 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 H52 I53 G55 K58 Y61 D71 E81 Y82 D83 P84 N85 R86 S87 L94 K96 D97 G98 E99 R100 M145 K146 P147 G148 K149 G151 Q152 L153 R155 S156 A157 Y170 L175 R176 S177 E179 R181 E184 D186 A197 M200 R202 V203 L204 G205 K206 A207 G208 R211 W212 R213 V215 R216 P217 T218 V219 R220 G221 T222 A223 M224 N225 P226 V227 D228 H229 P230 H231 G232 G233 G234 E235 G236 R237 N238 F239 G240 K241 H242 P243 V244 P246 W247 G248 Q250 T251 K252 G253 K254 K255 T256 R257 S258 N259 K260 R261 T262 D263 K264 F265 I266 R269 R270 S271 K272 |
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| Enzyme Commision number |
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