Structure of PDB 7uqu Chain BBB Binding Site BS01

Receptor Information
>7uqu Chain BBB (length=108) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNDNDPTFRNLPFVAEILEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVG
MPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLT
VRVLDVND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7uqu Chain BBB Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7uqu Crystal Structure of Mouse Cadherin-23 EC9
Resolution1.976 Å
Binding residue
(original residue number in PDB)		N861 N863 D893 D895 N899 D946
Binding residue
(residue number reindexed from 1)		N2 N4 D34 D36 N40 D87
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7uqu, PDBe:7uqu, PDBj:7uqu
PDBsum7uqu
PubMed
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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