Structure of PDB 7r1o Chain BBB Binding Site BS01

Receptor Information

>7r1o Chain BBB (length=48) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSP

Ligand information

>7r1o Chain EEE (length=5) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

RIVPA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7r1o Dusquetide modulates innate immune response through binding to p62.
Resolution	2.202 Å
Binding residue (original residue number in PDB)	H160 G162 H163
Binding residue (residue number reindexed from 1)	H37 G39 H40

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0008270	zinc ion binding

View graph for
Molecular Function

External links

PDB	RCSB:7r1o, PDBe:7r1o, PDBj:7r1o
PDBsum	7r1o
PubMed	35640615
UniProt	Q13501\|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

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