Structure of PDB 7b6s Chain BBB Binding Site BS01

Receptor Information

>7b6s Chain BBB (length=260) Species: 1634381 (Sheep polyomavirus 1)

IEVLAVRDSITEIEAYLNPRMGQPQNEDFYGFSDNVTVSDDFGSDAPPWK
QFPCYSTARISLPMLNTILMWEAISCRTEVMGVNMLTNVHSAQKRVYEND
REGTGIGVEGMGYHMFAIGGEPLELQFMVFNHRATYPAEATVIKNPGASS
QVFDPNLKGTLTADGVFPVEAWGPDPFKNENTRYFGQYTGGTQTPPVLTF
TNTQTTILLDENGVGPLCKGDGLFLSCADIVGFFTQHNKKMSFRGLPRYF
RVTLRKRVVK

Ligand information

• Ligand ID: GLA
• InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-PHYPRBDBSA-N
• SMILES:
  CACTVS 3.341: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O
  OpenEye OEToolkits 1.5.0: C(C1C(C(C(C(O1)O)O)O)O)O
  OpenEye OEToolkits 1.5.0: C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
  CACTVS 3.341: OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
  ACDLabs 10.04: OC1C(O)C(OC(O)C1O)CO
• Formula: C6 H12 O6
• Name: alpha-D-galactopyranose;
  alpha-D-galactose;
  D-galactose;
  galactose;
  ALPHA D-GALACTOSE
• ChEMBL: CHEMBL1233058
• ZINC: ZINC000000901155
• PDB chain: 7b6s Chain BaB Residue 2

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7b6s A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
• Resolution: 1.923 Å
• Binding residue (original residue number in PDB): D58 N59 K270
• Binding residue (residue number reindexed from 1): D34 N35 K240
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005198 structural molecule activity

Cellular Component

• GO:0019028 viral capsid

External links

• PDB: RCSB:7b6s, PDBe:7b6s, PDBj:7b6s
• PDBsum: 7b6s
• UniProt: A0A0E3ZCF3