Structure of PDB 7qo2 Chain BA Binding Site BS01

Receptor Information
>7qo2 Chain BA (length=222) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLPKSVDWRKKGYVTPVKNQKQCGSAWAFSATGALEGQMFRKTGKLVSLS
EQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK
YRPENSVAQDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKS
GIYFEPDCSSKNLDHGVLVVGYGFEGANSQNSKYWLVKNSWGPEWGSNGY
VKIAKDKNNHCGIATAASYPNV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qo2 Peptide GAKSAA in complex with human cathepsin V C25A mutant
Resolution1.77 Å
Binding residue
(original residue number in PDB)		G246 A248 Q286 G290 G291 F292 A359 D386 H387
Binding residue
(residue number reindexed from 1)		G24 A26 Q64 G68 G69 F70 A137 D164 H165
Enzymatic activity
Enzyme Commision number 3.4.22.43: cathepsin V.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qo2, PDBe:7qo2, PDBj:7qo2
PDBsum7qo2
PubMed
UniProtO60911|CATL2_HUMAN Cathepsin L2 (Gene Name=CTSV)

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