Structure of PDB 7qns Chain BA Binding Site BS01

Receptor Information
>7qns Chain BA (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPKSVDWRKKGYVTPVKNQKQCGSSWAFSATGALEGQMFRKTGKLVSLSE
QNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKY
RPENSVAQDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG
IYFEPDCSSKNLDHGVLVVGYGFEGANSQNSKYWLVKNSWGPEWGSNGYV
KIAKDKNNHCGIATAASYPNV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qns Peptide VYEKKP in complex with human cathepsin V C25S mutant
Resolution1.4 Å
Binding residue
(original residue number in PDB)		G245 S247 G289 G290 F291 A358 D385 H386
Binding residue
(residue number reindexed from 1)		G23 S25 G67 G68 F69 A136 D163 H164
Enzymatic activity
Enzyme Commision number 3.4.22.43: cathepsin V.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qns, PDBe:7qns, PDBj:7qns
PDBsum7qns
PubMed
UniProtO60911|CATL2_HUMAN Cathepsin L2 (Gene Name=CTSV)

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