Structure of PDB 7qhj Chain BA Binding Site BS01

Receptor Information
>7qhj Chain BA (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPKSVDWRKKGYVTPVKNQKQCGSAWAFSATGALEGQMFRKTGKLVSLSE
QNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKY
RPENSVAQDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG
IYFEPDCSSKNLDHGVLVVGYGFEGANSQNSKYWLVKNSWGPEWGSNGYV
KIAKDKNNHCGIATAASYPNV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qhj Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		G244 A246 W247 G289 D384
Binding residue
(residue number reindexed from 1)		G23 A25 W26 G68 D163
Enzymatic activity
Enzyme Commision number 3.4.22.43: cathepsin V.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qhj, PDBe:7qhj, PDBj:7qhj
PDBsum7qhj
PubMed37095140
UniProtO60911|CATL2_HUMAN Cathepsin L2 (Gene Name=CTSV)

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