Structure of PDB 4v7j Chain B9 Binding Site BS01

Receptor Information
>4v7j Chain B9 (length=37) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG
Ligand information
>4v7j Chain BA (length=2848) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga
cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc
uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc
uuuugcgcggggggaaccuggggaacugaaacaucucaguacccagagga
gaggaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccag
ccuaaaccguccggcuuguccgggcggggucgggggcccucggacaccga
auccccagccuagccgaagcuguugggaagcagcgccagagagggugaaa
gccccguaggcgaaagguggggggauaggugaggguacccgaguaccccg
ugguucguggagccaugggggaaucugggcggaccaccgccuaaggcuaa
guacuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaa
gaaccccgggaggggagugaaauagagccugaaaccgugggcuuacaagc
agucacggccccgcaagggguuguggcgugccuauugaagcaugagccgg
cgacucacggucgugggcgagcuuaagccguugaggcggaggcguaggga
aaccgaguccgaacagggcgcaagcgggccgcacgcggcccgcaaagucc
gcggccguggacccgaaaccgggcgagcuagcccuggccagggugaagcu
ggggugagacccaguggaggcccgaaccggugggggaugcaaaccccucg
gaugagcuggggcuaggagugaaaagcuaaccgagcccggagauagcugg
uucuccccgaaaugacuuuagggucagccucaggcgcugacuggggccug
uagagcacugauagggcuagggggcccaccagccuaccaaacccugucaa
acuccgaagggucccagguggagccugggagugagggcgcgagcgauaac
guccgcguccgagcgcgggaacaaccgagaccgccagcuaaggcccccaa
gucugggcuaagugguaaaggauguggcgccgcgaagacagccagucgag
uggcgccgcgccgaaaaugaucggggcuuaagcccagcgccgaagcugcg
ggucugggggaugaccccaggcgguaggggagcguucccgaugccgauga
aggccgacccgcgagggcggcuggagguaagggaagugcgaaugccggca
ugaguaacgauaaagagggugagaaucccucucgccguaagcccaagggu
uccuacgcaauggucgucagcguaggguuaggcgggaccuaaggugaagc
cgaaaggcguagccgaagggcagccgguuaauauuccggcccuucccgca
ggugcgauggggggacgcucuaggcuagggggaccggagccauggacgag
cccggccagaagcgcagggugggagguaggcaaauccgccucccaacaag
cucugcgugguggggaagcccguacgggugacaaccccccgaagccaggg
agccaagaaaagccucuaagcacaaccugcgggaacccguaccgcaaacc
gacacaggugggcgggugcaagagcacucaggcgcgcgggagaacccucg
ccaaggaacucugcaaguuggccccguaacuucgggagaaggggugcucc
cuggggugaugagccccggggagccgcagugaacaggcucuggcgacugu
uuaccaaaaacacagcucucugcgaacucguaagaggagguauagggagc
gacgcuugcccggugccggaaggucaaggggaggggugcaagccccgaac
cgaagccccggugaacggcggccguaacuauaacgguccuaagguagcga
aauuccuugucggguaaguuccgaccugcacgaaaagcguaacgaccgga
gcgcugucucggcgagggacccggugaaauugaacuggccgugaagaugc
ggccuacccguggcaggacgaaaagaccccguggagcuuuacugcagccu
gguguuggcucuuggucgcgccugcguaggauaggugggagccugugaac
ccccgccuccgggugggggggaggcgccggugaaauaccacccuggcgcg
gcugggggccuaacccucggauggggggacagcgcuuggcgggcaguuug
acuggggcggucgccuccuaaaagguaacggaggcgcccaaagguccccu
caggcgggacggaaauccgccggagagcgcaaggguagaagggggccuga
cugcgaggccugcaagccgagcaggggcgaaagccgggccuagugaaccg
guggucccguguggaagggccaucgaucaacggauaaaaguuaccccggg
gauaacaggcugaucucccccgagcguccacagcggcggggagguuuggc
accucgaugucggcucgucgcauccuggggcugaagaaggucccaagggu
ugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgu
gagacaguucggucucuauccgccacgggcgcaggaggcuugaggggggc
ucuuccuaguacgagaggaccggaagggacgcaccucugguuucccagcu
gucccuccaggggcauaagcuggguagccaugugcggaagggauaaccgc
ugaaagcaucuaagcgggaagcccgccccaagaugaggccucccacggcg
ucaagccgguaaggacccgggaagaccacccgguggaugggccgggggug
uaagcgccgcgaggcguugagccgaccggucccaaucguccgaggucu
<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<
<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>
>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<<
....>>>>>>.>>....<<<<<.....<<....>>......>>>>>....
.......<<....>>...<<<<<.....<<.....>>....>>>>>...<
<<....<<<<<<<<.....>>>>>>>>.....<<<<<<<<<....<<<..
.<<<<..<<<<.<<<...<<<<<......>>>>>((......<<<.....
))>>>...>>>...>>>>...>>>>..>>>>>>>>>.>>>.....<<<<<
<<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>...
...>>.>>>>>>.>>...............<<....>>....>>......
...<<<<....>>>>..................>>>>>>>>>>>......
.<<<<<<<<<<<....>>>>>>>>>>>...<............>.<<<<<
<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<..
..>>..<<<<.....>>>>.....<<<<.<<....>>.>>>>....>>>>
>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<
<<<......>>>>>>.....>>>...<<<<.<<<<........>>>>>>>
>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>
..<<<<<<....<<<<<....>>>>><<<<<<<<<.....<<<<<<<<<.
..<<<...<<<<<<<<...<<<<<<......>>>>.>>...>>>>>>>>.
.>>.>...>>>>>>>>>.....>>>>>>>.>>..<<<<<<<.<<......
>>.>>>>>>>.....<<<......>>>...<<<<.<<<...<<<(((...
..<<<<<<...........<<..<<<<<<<<<........<....>....
>>>>>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>
><<<<<<<<.....>>>>>>>>....>>>>>>..<<<<<...<<<.....
.<<<<<.<<<....>>>>>>>>...>>>..>>>>>........>>>>>><
......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<..
.<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<
<....>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<
<<<<<...<<<<....<<<<<.<<<..<<<<<.<<<<.<<..[[[[...>
>>>>><<<...<<<<<<<<<<<<<<<<.<<.....>>>>>>>>>.....>
>>>>>>>>..>>><...<<<<....>>>>.....>>>>>>...>>>..>>
>>>.........>>>>...>>...>>>>>>>>>>>>>>>..>>.....<<
......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<
<<.<<.........<.....<<<<<.....<..>......>>>>><<<<<
<<<<<<<.....>>>>>>>>>>>>............<<<<<<<<<..<<<
.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>
.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>
>...>>>>>>>>..>>>>><<<<<<.......>>>>>>........<...
........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>
>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>
>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.
<<<<<.<<<<<<<<<<<<<<<<...........<<<<<..<<<......<
<<<<<<<....>>>>>>>>...>>>............>>>>>..>>>>>>
>>>>>>>>>>...<<<<<....>>>>>....>>>>>.>>>..>>>>>..<
<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>...
<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<
<<<<<.<<..))))..>>>>>>>>>.............>>>>..>>>>>>
.......<<<<...<<<<<<...<<.......>>...>>>>>>....>>>
.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.
<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<
<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<
<<<<<]]]]>>>>>>...>>>>>...>>>>.>>>>>...<<<....<<<<
<...........>>>>>....>>>.>>>>.......>>>>>>>...<...
......>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<.
...<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>
Receptor-Ligand Complex Structure
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PDB4v7j The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 R22 P30 K31 K33 R35 Q36 G37
Binding residue
(residue number reindexed from 1)		M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 R22 P30 K31 K33 R35 Q36 G37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v7j, PDBe:4v7j, PDBj:4v7j
PDBsum4v7j
PubMed20005802
UniProtQ5SHR2|RL36_THET8 Large ribosomal subunit protein bL36 (Gene Name=rpmJ)

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