Structure of PDB 6lqp Chain B8 Binding Site BS01

Receptor Information
>6lqp Chain B8 (length=477) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPPDEEEQLLAKFVFGDTTDLQENLAKFNADFEAAWIDSDDEKIKVPILV
TNKTKKLRTSYNESKINGVHYINRLRSQFEKIYPRPKWVDDESDINALTK
ILSTTYNYKDTLSNSKLLPPKKLDIVRLKDANASHPSHSAIQSLSFHPSK
PLLLTGGYDKTLRIYHIDGKTNHLVTSLHLVGSPIQTCTFYTSLSNQNQQ
NIFTAGRRRYMHSWDLSLTAKIEKFSRLYGHESTQRSFENFKVAHLQNSQ
TNSVHGIVLLQGNNGWINILHSTSGLWLMGCKIEGVITDFCIDYQPISRG
KFRTILIAVNAYGEVWEFDLNKNGHVIRRWKDQGGVGITKIQVGGGTTTT
CPALQISKIKQNRWLAVGSESGFVNLYDRNNAMTSSTPTPVAALDQLTTT
ISNLQFSPDGQILCMASRAVKDALRLVHLPSCSVFSNWPTSGTPLGKVTS
VAFSPSGGLLAVGNEQGKVRLWKLNHY
Ligand information
>6lqp Chain 3A (length=175) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccagugagaaauugccguugcuauggcgcgaugaucacccaugggu
ggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<..<.........<<<<......>>>>.......>.<<<<..>>>>
.>>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqp Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K231 Q513 R542 S553
Binding residue
(residue number reindexed from 1)		K121 Q396 R425 S436
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000292 RNA fragment catabolic process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lqp, PDBe:6lqp, PDBj:6lqp
PDBsum6lqp
PubMed32943522
UniProtP40362|UTP18_YEAST U3 small nucleolar RNA-associated protein 18 (Gene Name=UTP18)

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