Structure of PDB 6ztm Chain B6 Binding Site BS01

Receptor Information

>6ztm Chain B6 (length=38) Species: 562 (Escherichia coli)

MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG

Ligand information

>6ztm Chain BA (length=2901)

gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacagaucugu
gugacugcguaccuuuuguauaaugggucagcgacuuauauucuguagca
agguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggcgu
uaaguugcaggguauagacccgaaacccggugaucuagccaugggcaggu
ugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaaaa
auuagcggaugacuuguggcugggggugaaaggccaaucaaaccgggaga
uagcugguucuccccgaaagcuauuuagguagcgccucgugaauucaucu
ccggggguagagcacuguuucggcaagggggucaucccgacuuaccaacc
cgaugcaaacugcgaauaccggagaauguuaucacgggagacacacggcg
ggugcuaacguccgucgugaagagggaaacaacccagaccgccagcuaag
gucccaaagucaugguuaagugggaaacgaugugggaaggcccagacagc
caggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagcuc
acuggucgagucggccugcgcggaagauguaacggggcuaaaccaugcac
cgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguucug
uaagccugugaaggugugcugugaggcaugcuggagguaucagaagugcg
aaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccggaa
gaccaaggguuccuguccaacguuaaucggggcagggugagucgaccccu
aaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccugu
acuugguguuacugcgaaggggggacggagaaggcuauguuggccgggcg
acgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccgga
aaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaacaa
augcccugcuuccaggaaaagccucuaagcaucagguaacaucaaaucgu
accccaaaccgacacagguggucagguagagaauaccaaggcgcuugaga
gaacucgggugaaggaacuaggcaaaauggugccguaacuucgggagaag
gcacgcugauauguaggugaggucccucgcggauggagcugaaaucaguc
gaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugcaa
acacgaaaguggacguauacggugugacgccugcccggugccggaagguu
aauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaaac
ggcggccguaacuauaacgguccuaagguagcgaaauuccuugucgggua
aguuccgaccugcacgaauggcguaaugauggccaggcugucuccacccg
agacucagugaaauugaacucgcugugaagaugcaguguacccgcggcaa
gacggaaagaccccgugaaccuuuacuauagcuugacacugaacauugag
ccuugauguguaggauaggugggaggcuuugaaguguggacgccagucug
cauggagccgaccuugaaauaccacccuuuaauguuugauguucuaacgu
ugacccgugauccggguugcggacagugucugguggguaguuugacuggg
gcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauccu
ggucggacaucaggagguuagugcaauggcauaagccagcuugacugcga
gcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugguu
cugaauggaagggccaucgcucaacggauaaaagguacuccggggauaac
aggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccucg
augucggcucaucacauccuggggcugaaguaggucccaaggguauggcu
guucgccauuuaaagugguacgcgagcuggguuuagaacgucgugagaca
guucggucccuaucugccgugggcgcuggagaacugaggggggcugcucc
uaguacgagaggaccggaguggacgcaucacugguguucggguugucaug
ccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagc
aucuaagcacgaaacuugccccgagaugaguucucccugacuccuugaga
guccugaaggaacguugaagacgacgacguugauaggccggguguguaag
cgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaacc
u

<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[..(((.>>>.....<<<<<<<..<<<)))..].>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]].....
..........<<....>>....]].........<<<<.....>>>>....
..............>>>>>>>>>>>.......<<<<..<<<<<<..>>>>
>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<.
.<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>..
...>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<
....<<<<<<......>>>>>>.....>>>...<<<.<<<<<........
>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...
...>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<
<<<<.....<<<...<<<.<<<<...<<.<<<.......>>>..>>...>
>>>.>>>..>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<
<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<...<
<<(((.....<<<<<<...........<<..<<<<<..<<........<<
<<<.<<...<<<.........>>>...>>........<<<......>>>.
.>>>>>....>>..>>>>>.>>...........))).....>>>>>>.>>
>...>>>>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<
...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>.....
...>>>>>><......<<.....<<<<<<.......>>>>>><<<<....
<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<.
..<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>>
))<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<..
..(((...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>
>>>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>>.
..>>>...>>>>.........>>>>...>>....>>>>>>>>>>>.>>>.
.>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<.
...<<<<<<<<.<<...............<<<<<...............>
>>>><<<<<<.....<<<...<<<<.....>>>>...>>>...>>>>>>.
...........<<<<<<<<<..<<<.........>>>..<<<<<<<....
.<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<.
...<...<<<<<..<<....>>...>>>>>.>......>>>>>>>>..>>
>>><<<<<<.......>>>>>>........<...........<<<<<<..
...>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>>>>
>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(
((.[[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<
..<<<............<<<<<..<<<......<<<<<<<<....>>>>>
>>>...>>>............>>>>>...>>>..>>>>>>>>>>...<<<
.<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<...
..>>>><<<<<<...........>>>>>>.(<<...<<<<<<<...<<<<
<<.......>>>>>>.....<<)..(((>>....>>>>>>>...<<<<..
<<<<....>>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.
((..>>>>..))>>>>>>>.............>>>>..]]>>>>......
.<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>....
...<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.
....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.
>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<
...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<)
)).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<......
.....>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>
>>>.....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>.....>>.....>>>>>>>>
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ztm Structural basis of transcription-translation coupling and collision in bacteria.
• Resolution: 3.3 Å
• Binding residue (original residue number in PDB): M1 K2 R4 A5 S6 V7 K8 L10 I16 K18 R19 D20 R24 K32 K34 R36 Q37 G38
• Binding residue (residue number reindexed from 1): M1 K2 R4 A5 S6 V7 K8 L10 I16 K18 R19 D20 R24 K32 K34 R36 Q37 G38

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ztm, PDBe:6ztm, PDBj:6ztm
• PDBsum: 6ztm
• PubMed: 32820062
• UniProt: P0A7Q6|RL36_ECOLI Large ribosomal subunit protein bL36A (Gene Name=rpmJ)