Structure of PDB 6ke6 Chain B6 Binding Site BS01

Receptor Information
>6ke6 Chain B6 (length=374) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKTRYYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSIN
DYIKYINYESNVNKLRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGTN
KFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCA
KYEYEVHANFKSCRNIFQNGLRFNPDVPKLWYEYVKFELNFITKLINRRK
VMGLINALRGDIALTIFDVCMKTLGKHYINKHKGYYAISDSKMNIELNKE
TLNYLFSESLRYIKLFDEFLDLERDYLINHVLQFWKNDMYDLSLRKDLPE
LYLKTVMIDITLNIRYMPVEKLDIDQLQLSVKKYFAYISKLDSASVKSLK
NEYRSYLQDNAEDDPRYKILDLII
Ligand information
>6ke6 Chain 5A (length=522) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcagugaagacaaguggcuugucguucguuaaaauggccucgu
caaacgguggagagagucgcuaggugaucgucagaucugccuagucucua
uacagcguguuuaauugacauggguugaugcguauugagagauacaauuu
gggaagaaauucccagaguguguuucuuuugcguuuaaccugaacagucu
caucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggugg
auuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaaug
ccuuguugaauagccggucgcaagacugugauucuucaaguguaaccucc
ucucaaaucagcgauaucaaacguaccaccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaugguga
cggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuuc
cggcagcagagauuucagcugu
<<<....>>>..<<<<<<<<<<.>>>>>>>.>>>..............<<
<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>.
..>>.>>>......>>>>>..<<<<<..........<<<<<<<<<<.<<<
<<<<<....>>>>>>>>.>>>>>>>>>>........>>>>>.......<<
<<<<<<<<<...........>>>>>.>>>>>>..................
.......<<<...>>>.........................<<<<<...<
<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>..>>>>>
.....<<<<<<...<<<<<<<<<<<<<.<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.................................
<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>>.>>
>>.<<<<.<<<..>>>.>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ke6 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K3 Y6 Y7 Q10 R46 K79 N81 L83 W86 Q90 F94 Q97 K102 R120 Q123 T124 Y126
Binding residue
(residue number reindexed from 1)		K2 Y5 Y6 Q9 R45 K78 N80 L82 W85 Q89 F93 Q96 K101 R119 Q122 T123 Y125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
GO:0042802 identical protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ke6, PDBe:6ke6, PDBj:6ke6
PDBsum6ke6
PubMed
UniProtQ02354|UTP6_YEAST U3 small nucleolar RNA-associated protein 6 (Gene Name=UTP6)

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