Structure of PDB 6gaw Chain B2 Binding Site BS01

Receptor Information
>6gaw Chain B2 (length=179) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNML
LTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEK
ARPGAWRRDIFGRIIWHKFKQWPIPWYLNKKYNRKRFFAMPYVERFVRMR
IEKQARIKARKRSLERKKEKFLQEKFPHL
Ligand information
>6gaw Chain BA (length=1549) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacua
acuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaa
acccuccgagugauuuuaaucuagacaaaccagucaaaauaaccauaaca
ucacuuauugauccaaaauuuugaucaacggaacaaguuacccuagggau
aacagcgcaauccuguucuagaguuccuaucgacaauaggguuuacgacc
ucgauguuggaucaggacacccaaauggugcaaccgcuauuaaagguucg
uuuguucaacgauuaaaguccuacgugaucugaguucagaccggagcaau
ccaggucgguuucuaucuauuauaaauuucucccaguacgaaaggacaag
agaaaugggaccaaccucacaaacgcgucucagagauaauuaaugauuua
aucuuaaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<......<<<<....................................
...<......>.................<<.....>>.............
.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<...<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>....
..>.>>..<<<<<.....<<<<....>>>>...<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>......<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<<..>>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>....<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>....>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<......>>
>>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<........
...>>>>>>.<<<<....<<...<<<......>>>...>>.........>
>>>..........<<<....>>>............>>>>..>>>>>>...
....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.
......<<<<<..<<<<<..<<.<<<<<<......>>>>>>...>>.<<<
<<.....>>>>>.....>>>>>......>>>.>>....<<<<<<<....>
>>.>>>>....>>..>>>>>>.<<.<<<<<<<.................>
>>>>>><<<<<...............>>>>>.<<<...<<<<.<......
......>..>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gaw Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q119 R123 R125 R166 R172 G176 K182 K184 P187 I188 Y191 L192 K194 R198 K199 R200 F202 R214 I215 R224 R226 R230 K231 K232 K234
Binding residue
(residue number reindexed from 1)		Q55 R59 R61 R102 R108 G112 K118 K120 P123 I124 Y127 L128 K130 R134 K135 R136 F138 R150 I151 R160 R162 R166 K167 K168 K170
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005761 mitochondrial ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gaw, PDBe:6gaw, PDBj:6gaw
PDBsum6gaw
PubMed30089917
UniProtF1SGC7

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