Structure of PDB 6gaw Chain B1 Binding Site BS01

Receptor Information
>6gaw Chain B1 (length=244) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLHKVPVGLWKQLRLWEGIYSRLPRHYLRSLEEARTPTPVHYRPHGAKFK
INPKNWQRERVEDVPIPVHYPPESQLGLWGGEGWVLGHRYVNNDKLSKRV
RKVWKPQLFQRELYSEILDKRFTVTVTMRTLDLIDQACGFDFYILKTPKE
DLCSKFGMDLKRGMLLRLARQDPQLHPDDPARRAAIYDRYKAFVIPEAEA
EWVGLTLDEAVEKQRLLEEKDPIPLFKIFVEELLGQLQQQALSE
Ligand information
>6gaw Chain BA (length=1549) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacua
acuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaa
acccuccgagugauuuuaaucuagacaaaccagucaaaauaaccauaaca
ucacuuauugauccaaaauuuugaucaacggaacaaguuacccuagggau
aacagcgcaauccuguucuagaguuccuaucgacaauaggguuuacgacc
ucgauguuggaucaggacacccaaauggugcaaccgcuauuaaagguucg
uuuguucaacgauuaaaguccuacgugaucugaguucagaccggagcaau
ccaggucgguuucuaucuauuauaaauuucucccaguacgaaaggacaag
agaaaugggaccaaccucacaaacgcgucucagagauaauuaaugauuua
aucuuaaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<......<<<<....................................
...<......>.................<<.....>>.............
.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<...<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>....
..>.>>..<<<<<.....<<<<....>>>>...<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>......<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<<..>>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>....<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>....>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<......>>
>>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<........
...>>>>>>.<<<<....<<...<<<......>>>...>>.........>
>>>..........<<<....>>>............>>>>..>>>>>>...
....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.
......<<<<<..<<<<<..<<.<<<<<<......>>>>>>...>>.<<<
<<.....>>>>>.....>>>>>......>>>.>>....<<<<<<<....>
>>.>>>>....>>..>>>>>>.<<.<<<<<<<.................>
>>>>>><<<<<...............>>>>>.<<<...<<<<.<......
......>..>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gaw Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		L3 K5 V6 L10 W11 H70 L87 G88 H89 Y91 K96 S98 K99 R100 R102 K103 K106 Q108 F110 R112
Binding residue
(residue number reindexed from 1)		L2 K4 V5 L9 W10 H69 L86 G87 H88 Y90 K95 S97 K98 R99 R101 K102 K105 Q107 F109 R111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6gaw, PDBe:6gaw, PDBj:6gaw
PDBsum6gaw
PubMed30089917
UniProtA0A286ZTW8

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