Structure of PDB 9fil Chain B Binding Site BS01
Receptor Information
>9fil Chain B (length=418) Species:
224324
(Aquifex aeolicus VF5) [
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MRSYPAIPRIYAETTLNMLLKRAKKPRVHSIDEYLKDGGYQALEKALNMS
PEEIIDWVDKSTLRGRGGAGFPTGKKWKFAVQNPGPRYFICNADESEPGT
FKDRIIIERDPHLLIEGIIISSYAIGANEAYIYIRGEYPAGYYILRDAIE
EAKKKGFLGKNILGSGFDLEIYVARGAGAYICGEETALIESLEGKRGHPR
LKPPYPVQKGLWGKPTVVNNVKTIANVPFIISMGWEEYRYIGPSDYAGPK
LFPVSGKVKKPGVYELPMNTTLREVIFKYAGGTLGNKKVKAVFSGALDCF
SSEELDIPMDYSPLGFGGTGTVIVLTEEDDIVEAALKIAEFYEHETCGQC
TPCRVGCYEQANLLEKIYKGEATEQDWEGFDFVNRNIQPTSICGLGAVAG
RLIRQTLEKFPEEWEKYR
Ligand information
Ligand ID
SF4
InChI
InChI=1S/4Fe.4S
InChIKey
LJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
Software
SMILES
OpenEye OEToolkits 2.0.7
[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385
S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
Formula
Fe4 S4
Name
IRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain
9fil Chain B Residue 501 [
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Receptor-Ligand Complex Structure
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PDB
9fil
Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I).
Resolution
2.54 Å
Binding residue
(original residue number in PDB)
P199 T346 C347 G348 Q349 C350 C353 I392 C393 G396
Binding residue
(residue number reindexed from 1)
P199 T346 C347 G348 Q349 C350 C353 I392 C393 G396
Annotation score
1
Gene Ontology
Molecular Function
GO:0046872
metal ion binding
GO:0048038
quinone binding
GO:0051539
4 iron, 4 sulfur cluster binding
Biological Process
GO:1902600
proton transmembrane transport
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Molecular Function
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Biological Process
External links
PDB
RCSB:9fil
,
PDBe:9fil
,
PDBj:9fil
PDBsum
9fil
PubMed
38960077
UniProt
O66841
|NUOF_AQUAE NADH-quinone oxidoreductase subunit F (Gene Name=nuoF)
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