Structure of PDB 9f37 Chain B Binding Site BS01

Receptor Information
>9f37 Chain B (length=736) Species: 11320 (Influenza A virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYS
SRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHP
GLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF
RKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFGKKRVKLTKKNYLIR
ALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSG
LPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLA
MVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISA
ENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLG
VSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTC
KLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNES
ADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLET
RRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDY
RGRLCNPNNPFVHHMEVESTNLAVVMPAHGPAKSLEYDAVATTHSWTPKR
NRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLS
RARIDARIDLESGRISSQDFSEITNTCKAIEALKRQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9f37 High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit
Resolution1.905 Å
Binding residue
(original residue number in PDB)
G125 R126 Q127 R135 N136 K229 D230 I241 A242 T243 R249 R353 M409 G410 N413 P651 N671 R672 S673 I674 N676
Binding residue
(residue number reindexed from 1)
G125 R126 Q127 R135 N136 K209 D210 I221 A222 T223 R229 R333 M389 G390 N393 P631 N651 R652 S653 I654 N656
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