Structure of PDB 9b6k Chain B Binding Site BS01

Receptor Information
>9b6k Chain B (length=919) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLVNFIQANFKDAFGDIQGKYLRLSCDTDSETLYELLTQHWHLKTPNLVI
SVTRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISENIV
AIGIAAWGMVSNRDTFSAQYIMLYILDNNHTHLLLVDNGCHGHPTVEAKL
RNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCV
VVEGSGQIADVIASLVTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKE
ILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQDKDNWNGQLKLL
LEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLN
LQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRR
SFTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKV
KNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLLVYSCEAWGGS
NCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPL
VGCGLVSFRKLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSV
PHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGI
VFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRM
LIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFG
QVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPEWITIPLVCIY
MLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPF
PFVVFAYFYMVVKKNETLAWEGVMKENYLVKINTKANDNSEEMRHRFRQL
DSKLNDLKSLLKEIANNIK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain9b6k Chain B Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9b6k Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
Resolution4.13 Å
Binding residue
(original residue number in PDB)		E782 N799 R842
Binding residue
(residue number reindexed from 1)		E619 N636 R679
Annotation score4
External links
PDB RCSB:9b6k, PDBe:9b6k, PDBj:9b6k
PDBsum9b6k
PubMed39093967
UniProtQ8R4D5|TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (Gene Name=Trpm8)

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