Structure of PDB 8xrf Chain B Binding Site BS01

Receptor Information

>8xrf Chain B (length=774) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITIMVRNEQLTNNKVLQGIVQVLGLDFNC
HYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGF
VKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGLA
AHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGV
VPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRAR
RKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQY
YPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAED
SWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDI
LALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYY
SYGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSS
SETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKP
KGGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYI
NESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKAL
QGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGAS
VWLEEIDAVEKAIIKGRNTQWKFH

Ligand information

>8xrf Chain D (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgcggtagcagtagg

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8xrf The crystal structure of AsfvTopII in complex with G-DNA
Resolution	2.94 Å
Binding residue (original residue number in PDB)	V473 M475 N476 K479 K480 Q498 K547 S657 R660 K661 Q706 R799 Y800 P852 S853 E854 G855 K857 S953 R1004 H1010
Binding residue (residue number reindexed from 1)	V61 M63 N64 K67 K68 Q80 K129 S239 R242 K243 Q288 R381 Y382 P434 S435 E436 G437 K439 S535 R586 H592

External links

PDB	RCSB:8xrf, PDBe:8xrf, PDBj:8xrf
PDBsum	8xrf
PubMed
UniProt	Q00942\|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

[Back to BioLiP]