Structure of PDB 8xa9 Chain B Binding Site BS01
Receptor Information
>8xa9 Chain B (length=214) Species:
9606
(Homo sapiens) [
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RVPQNWFPIFNPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMIL
ELGEDGFKEYTSNVFLQGKRFHEALESILSPSGYIESVQHILKDVSGVRA
LESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQ
VVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKW
LLRLEEYTEKKKNQ
Ligand information
>8xa9 Chain C (length=11) [
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tttttttgctg
Receptor-Ligand Complex Structure
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PDB
8xa9
Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity.
Resolution
2.32 Å
Binding residue
(original residue number in PDB)
S132 T134 Q138 Q144 Q145 F147 L148 L149 R151 W152 V172 F173 G176 K177 H180 G235 L236 K253 T254 F266 Y275
Binding residue
(residue number reindexed from 1)
S24 T26 Q30 Q36 Q37 F39 L40 L41 R43 W44 V64 F65 G68 K69 H72 G114 L115 K132 T133 F145 Y154
Enzymatic activity
Enzyme Commision number
3.1.-.-
External links
PDB
RCSB:8xa9
,
PDBe:8xa9
,
PDBj:8xa9
PDBsum
8xa9
PubMed
38471810
UniProt
Q9BQP7
|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)
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