Structure of PDB 8w8g Chain B Binding Site BS01

Receptor Information
>8w8g Chain B (length=206) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHG
LSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSI
EKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFK
SKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAA
KVVESK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w8g PinX1 suppress tumorigenesis through inhibiting telomerase activity
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R102 E106 I109 H110 S113 I123 Q127 R131 D139 A140 Q141 F142 E146 R147 E192
Binding residue
(residue number reindexed from 1)
R41 E45 I48 H49 S52 I62 Q66 R70 D78 A79 Q80 F81 E85 R86 E131
External links
PDB RCSB:8w8g, PDBe:8w8g, PDBj:8w8g
PDBsum8w8g
PubMed
UniProtP54274|TERF1_HUMAN Telomeric repeat-binding factor 1 (Gene Name=TERF1)

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