Structure of PDB 8w47 Chain B Binding Site BS01

Receptor Information
>8w47 Chain B (length=116) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLT
TEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAA
LLSPYSYSTTAVVTNP
Ligand information
Ligand IDP5O
InChIInChI=1S/C15H14O4/c1-19-15-8-10(4-5-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKeyANNNBEZJTNCXHY-NSCUHMNNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7COc1cc(ccc1O)/C=C/c2cc(cc(c2)O)O
OpenEye OEToolkits 2.0.7COc1cc(ccc1O)C=Cc2cc(cc(c2)O)O
CACTVS 3.385COc1cc(ccc1O)/C=C/c2cc(O)cc(O)c2
CACTVS 3.385COc1cc(ccc1O)C=Cc2cc(O)cc(O)c2
FormulaC15 H14 O4
Name5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol
ChEMBLCHEMBL110370
DrugBank
ZINCZINC000013541228
PDB chain8w47 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w47 Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		K15 L17 L110 S117 T118
Binding residue
(residue number reindexed from 1)		K6 L8 L101 S108 T109
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8w47, PDBe:8w47, PDBj:8w47
PDBsum8w47
PubMed37910439
UniProtP02766|TTHY_HUMAN Transthyretin (Gene Name=TTR)

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