Structure of PDB 8vs6 Chain B Binding Site BS01
Receptor Information
>8vs6 Chain B (length=349) Species:
9606
(Homo sapiens) [
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INTQVTPGEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNI
EKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSD
YNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQA
AVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLKNNV
YVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIA
GEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRK
PGMEGCRNVTSNDEVLFNVTVTMKKCDNYAIIKPIGFNETAKIHIHRNC
Ligand information
>8vs6 Chain E (length=10) Species:
9606
(Homo sapiens) [
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GRGDLGRLKK
Receptor-Ligand Complex Structure
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PDB
8vs6
Dynamic allostery drives autocrine and paracrine TGF-beta signaling
Resolution
2.73 Å
Binding residue
(original residue number in PDB)
A115 S116 C169 Y172 L174 G206 N207 I208 T210 E212
Binding residue
(residue number reindexed from 1)
A44 S45 C98 Y101 L103 G135 N136 I137 T139 E141
External links
PDB
RCSB:8vs6
,
PDBe:8vs6
,
PDBj:8vs6
PDBsum
8vs6
PubMed
UniProt
P26012
|ITB8_HUMAN Integrin beta-8 (Gene Name=ITGB8)
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