Structure of PDB 8vpg Chain B Binding Site BS01

Receptor Information
>8vpg Chain B (length=551) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDIL
YDLFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDS
LTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEK
KYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESL
SGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETF
YNKIQEKCKYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCW
IKSKNINKYIVDKSEYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRE
CKSGIRKWYELQWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVY
SFFIKEEYLDKFSYEYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVM
KIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLG
I
Ligand information
Receptor-Ligand Complex Structure
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PDB8vpg Quinoline-based compounds can inhibit diverse enzymes that act on DNA
Resolution3.05 Å
Binding residue
(original residue number in PDB)		Y30 N165 P166 Y168 H171 K173 K193 Y221 S227 F253 I256 G257 F345 Q346 R432 W439 R441 K456 Y476 K511 M513 S514 Y521 P522 N523
Binding residue
(residue number reindexed from 1)		Y4 N139 P140 Y142 H145 K147 K167 Y195 S201 F227 I230 G231 F319 Q320 R406 W413 R415 K430 Y450 K485 M487 S488 Y495 P496 N497
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