Structure of PDB 8vc5 Chain B Binding Site BS01

Receptor Information
>8vc5 Chain B (length=482) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTVRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDSTRESEQ
QIYDALRWLGIEWDEGPDVGGPHGPYRQSERGHIYKKYSDELVEKGHAFT
CFCTPERLDAVRAEQMARKETPRYDGHCMHLPKDEVQRRLAAGESHVTRM
KVPTEGVCVVPDMLRGDVEIPWDRMDMQVLMKADGLPTYFLANVVDDHLM
GITHVLRGEEWLPSAPKLIKLYEYFGWEQPQLCYMPLLRNPDKSKLSKRK
NPTSITFYERMGYLPQALLNYLGRMGWSEKFTLAEMIEHFDLSRVSLGGP
IFDLEKLSWLNGQWIREQSVEEFAREVQKWALNPEYLMKIAPHVQGRVEN
FSQIAPLAGFFFSGGVPLDASLFEHKKLDPTQVRQVLQLVLWKLESLRQW
EKERITGCIQAVAEHLQLKLRDVMPLMFPAITGHASSVSVLDAMEILGAD
LSRYRLRQALELLGGASKKETKEWEKIRDAIP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8vc5 Chain B Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8vc5 Crystal structure of glutamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa (Zinc bound)
Resolution2.3 Å
Binding residue
(original residue number in PDB)		C107 C109 Y130 C134
Binding residue
(residue number reindexed from 1)		C101 C103 Y124 C128
Annotation score1
Enzymatic activity
Enzyme Commision number 6.1.1.17: glutamate--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8vc5, PDBe:8vc5, PDBj:8vc5
PDBsum8vc5
PubMed
UniProtQ9XCL6|SYE_PSEAE Glutamate--tRNA ligase (Gene Name=gltX)

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