Structure of PDB 8var Chain B Binding Site BS01

Receptor Information
>8var Chain B (length=362) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVG
KTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTK
VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHV
KFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEP
RALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQAL
SLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPA
ALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVE
MTLLRALAFHPR
Ligand information
Receptor-Ligand Complex Structure
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PDB8var Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		T99 K100 V101 S132 H134
Binding residue
(residue number reindexed from 1)		T99 K100 V101 S132 H134
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8var, PDBe:8var, PDBj:8var
PDBsum8var
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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