Structure of PDB 8ufj Chain B Binding Site BS01

Receptor Information
>8ufj Chain B (length=444) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKCTTKEDVLEAVKERDVKFIRTQFTDTLGIIKSWAIPAEQLEEAFENG
VMFDGSSIQGFTRIEESDMKLALDPSTFRILPWRPATGAVARILGDVYLP
DGNPFKGDPRYVLKTAIKEAEKMGFSMNVGPELEFFLFKLDANGNPTTEL
TDQGGYFDFAPLDLGQDVRRDIDYALEHMGFQIEASHHEVAPSQHEIDFR
FGDVLCTADNVVTFKYVVKSIAYHKGYYASFMPKPLFGVNGSGMHSNQSL
FKDGKNVFYDPDTPTKLSQDAMYYIGGLLKHIREFTAVTNPVVNSYKRLV
PGYEAPVYISWSAQNRSSLIRIPATRGNGTRIELRCPDPACNPYLAFALM
LRAGLEGIKNKIDPGEPTNVNIFHLSDKEREERGIRSLPADLKEAIDEMK
GSKFVKEALGEHVFSHYLCAKEMEWDEYKAVVHPWELSRYLSML
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8ufj Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ufj M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		E137 E192 E199
Binding residue
(residue number reindexed from 1)		E134 E189 E196
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.1.2: glutamine synthetase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004356 glutamine synthetase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006542 glutamine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ufj, PDBe:8ufj, PDBj:8ufj
PDBsum8ufj
PubMed37968329
UniProtQ8PY99|GLNA1_METMA Glutamine synthetase (Gene Name=glnA1)

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