Structure of PDB 8ucv Chain B Binding Site BS01
Receptor Information
>8ucv Chain B (length=186) Species:
8355
(Xenopus laevis) [
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ISLEQIDGFAAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTL
EQALQFWRLEFTKGKVDSEKFDKVYAYSIRHNYGKEGKRTDYTPYSCMKV
ILSNPPSQGDYHGCPFRHSDPELLKQKLQSFKVPSSGINQILELVKGMHY
QLACQKYFELTHSVDDCGFSLNHPNQYFAESQKLLT
Ligand information
>8ucv Chain C (length=36) [
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tgtcgctacaatcgctaagttcacgcagtatcctgt
Receptor-Ligand Complex Structure
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PDB
8ucv
A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Resolution
3.81 Å
Binding residue
(original residue number in PDB)
M313 K349 Y353 H357 N358 G363 K364 T366 Y368 T369 Y371 S372 K375
Binding residue
(residue number reindexed from 1)
M37 K73 Y77 H81 N82 G87 K88 T90 Y92 T93 Y95 S96 K99
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0046872
metal ion binding
GO:0051539
4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006269
DNA replication, synthesis of primer
GO:0006270
DNA replication initiation
Cellular Component
GO:0005658
alpha DNA polymerase:primase complex
GO:1990077
primosome complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8ucv
,
PDBe:8ucv
,
PDBj:8ucv
PDBsum
8ucv
PubMed
38491139
UniProt
A0A1L8G3G3
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